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A new mechanism triggering cell death and inflammation: A left turn that kills

UNIVERSITY OF COLOGNE Z-form nucleic acids are double-stranded DNA and RNA molecules with an unusual left-handed double helix structure, as opposed to the classical right-handed Watson-Crick double helix. Z-nucleic acids were discovered more than 40 years ago, but their biological function has remained poorly understood. The group of Professor Manolis Pasparakis at the CECAD Cluster...