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7.2% of All Deaths Worldwide are Attributable to Physical Inactivity
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7.2% of All Deaths Worldwide are Attributable to Physical Inactivity

Humans evolved in an environment of physical exertion, and our biochemistry requires physical exertion in order to trigger mechanisms of cell maintenance and metabolic regulation. Populations that exercise vigorously into late old age, such as the Tsimane in Bolivia, exhibit very much lower levels of cardiovascular disease. Further, living a sedentary lifestyle shortens life expectancy and increases disease risk when compared...

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Genomic test helps estimate risk of prostate cancer metastasis, death

JOHNS HOPKINS MEDICINE A commercially available genomic test may help oncologists better determine which patients with recurrent prostate cancer may benefit from hormone therapy, according to new research from the Johns Hopkins Kimmel Cancer Center and 15 other medical centers. Researchers studied prostate cancer samples from 352 participants in the NRG/RTOG 9601clinical trial, which compared radiation therapy alone with...

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TWO-DRUG COMBO STARVES BONE CANCER CELLS TO DEATH

FEBRUARY 1ST, 2021POSTED BY JIM GOODWIN-WUSTL “In the future, we would like to add more metabolic therapies so that one day we might be able to eliminate the remaining chemotherapy drugs that these patients will still receive,” says Brian Van Tine. “The ultimate goal is to transform therapy by going after the metabolic properties that...

Vitamin D levels may predict future health risks, death in older men
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Vitamin D levels may predict future health risks, death in older men

Advances in science are helping researchers find new ways to identify diseases earlier. A new breakthrough indicates that free, circulating vitamin D levels in the bloodstream may be a good predictor of future health and disease risk in aging men. Low levels of vitamin D correlate with age-related health problems, including osteoporosis.Photo credit: Crevis/Adobe Stock...

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Protein produced by the nervous system may help treatments for inflammatory diseases

Rutgers researchers discovered a new role the protein may have in helping to treat allergies, asthma, COPD RUTGERS UNIVERSITY A Rutgers-led team may have found the key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD). In a study published in the journal Nature Immunology, researchers discovered that neuromedin...

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‘Good’ virus for common infection

Antibiotic-resistant diabetic foot ulcer application FLINDERS UNIVERSITY Australian researchers have shown how viruses can be used to save lives, developing the potential use of bacteriophages in bandages to treat life-threatening golden staph infections which may not respond to traditional antibiotics. Targeting multidrug-resistant Staphylococcus aureus (‘golden staph’) in diabetic foot ulcers, Flinders University microbiology researchers have...

Study Suggests Method to Starve Pancreatic Cancer Cells
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Study Suggests Method to Starve Pancreatic Cancer Cells

A University of Michigan-led study is shedding new light on the way pancreatic cancer cells turn nearby connective tissue cells into co-conspirators in their deadly growth. The findings, which appear in Nature Metabolism, also suggest a new potential strategy against pancreatic cancer by identifying critical components of metabolic cross-talk between cells that might be attacked...

Restoring nerve-muscle communication in ALS
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Restoring nerve-muscle communication in ALS

by Karuna Meda, Thomas Jefferson University Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, lose muscle control as nerve cells or neurons in the brain and spinal cord degenerate and can no longer send signals to muscles. Previous studies have identified that problems at the synapse, the point where signals jump...