by Shana K. Hutchins, Texas A&M University Translating human GWAS signals to functional outcomes with variant-to-gene mapping. (A) Leveraging existing insomnia human GWAS loci, we identified proxy SNPs in strong linkage disequilibrium with sentinel SNPs using both genome-wide ATAC-seq and high-resolution promoter-focused Capture C data from iPSC-derived NPCs and then performed high-throughput sleep and activity...
