NEWS RELEASE 2-JUL-2024 Study in mice focuses on ‘wet’ form of the eye disease Peer-Reviewed PublicationOHIO STATE UNIVERSITY COLUMBUS, Ohio – A new study in mice hints at the promise of an eventual alternative treatment option for the “wet” version of age-related macular degeneration (AMD). Researchers determined in mice that an enzyme related to cell...
Tag: <span>degeneration</span>
Post
Microscopic ‘nano-shuttles’ may help drive degeneration of brain cells, research suggests
by Nottingham Trent University Graphical abstract. Credit: Progress in Neurobiology (2022). DOI: 10.1016/j.pneurobio.2022.102313 Tiny “nano-shuttles” transport a damaging cargo around the brain where it goes on to play a role in the degeneration of cells, a study has suggested. Scientists at Nottingham Trent University and the National Research Council Institute of Neuroscience in Milan have established how...
Post
Research explores why certain brain neurons are vulnerable to degeneration
by The Ohio State University Credit: CC0 Public Domain Research led by neuroscientists at The Ohio State University College of Medicine provides insights into mechanisms that underpin selective neuronal vulnerability, which could help in developing new therapeutics to prevent and treat Alzheimer’s disease and other neurodegenerative diseases. Study findings are published online in the journal Acta...
Post
Researchers discover key mechanisms behind synapse degeneration in Alzheimer’s brain
by University of California – San Diego A. Localization of Wnt/PCP pathway signaling components in glutamatergic synapses in adult hippocampus detected by super-resolution microscopy. B. Schematic diagram showing the balance of Wnt/PCP signaling in synapse maintenance and the binding site of oligomeric amyloid beta. Credit: Feng et al., Sci. Adv. 2021 Healthy adult brains are endowed with...
Post
Genetic program protects neurons from degeneration
UNIVERSITY OF BONN IMAGE: IN THE LABORATORY: FIRST AUTHOR DR. AZADEH IZADIFAR AND PROF. DR. DIETMAR SCHMUCKER WITH CULTURE VESSELS CONTAINING FRUIT FLIES. CREDIT: © VOLKER LANNERT / UNIVERSITY OF BONN Researchers at the University of Bonn (Germany) have identified a previously unknown genetic program in the fruit fly. The genetic material involved controls the development...