by University of Helsinki Credit: Pixabay/CC0 Public Domain Psychotic-like experiences resemble symptoms of psychosis, but are milder, less frequent and much more common than psychotic disorders. While these symptoms do not constitute a disorder diagnosed as psychosis, they can still be disruptive, distressing or detrimental to functional capacity. Typical psychotic-like experiences include perceptual distortions and hallucinations,...
Tag: <span>Depression</span>
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Discovery reveals how low-dose ketamine, a ‘lifesaving’ drug for major depression, alleviates symptoms within hours
by Ellen Goldbaum, University at Buffalo These images demonstrate the different binding sites in NMDA receptors that the UB team has discovered are responsible for ketamine’s distinct clinical effects, as an anesthetic at high doses and as an anti-depressant at very low doses. The image on the left shows ketamine bound in the central pore of...
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Childhood neglect associated with later stroke, COPD, cognitive impairment, and depression
by University of Toronto Credit: Unsplash/CC0 Public Domain New research from the University of Toronto found that childhood neglect, even in the absence of childhood sexual abuse and physical abuse, is linked with a wide range of mental and physical health problems in adulthood. “While a large body of research has established the detrimental impact of childhood physical...
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Data analysis explores connection between inflammation and depression
by Annalena Huber, Max Planck Society In the study, biological data was gathered from participants. Based on different patterns in the data, the researchers grouped participants into four clusters. Credit: Janine Knauer-Arloth Roughly one-third of patients with depressive symptoms have elevated levels of inflammation. Inflammation is, however, often only measured using very broad and unspecific markers....
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Magnetic field applied to both sides of brain shows rapid improvement for depression
University of Cambridge A type of therapy that involves applying a magnetic field to both sides of the brain has been shown to be effective at rapidly treating depression in patients for whom standard treatments have been ineffective. The treatment – known as repetitive transcranial magnetic stimulation (TMS) – involves placing an electromagnetic coil against...
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Liver X receptor beta: A new frontier in treating depression and anxiety
October 4, 2024 by Genomic Press In a Bench to Bedside review published in the journal Brain Medicine, researchers Dr. Xiaoyu Song and Professor Jan-Åke Gustafsson from the University of Houston and Karolinska Institutet (Sweden) shed light on the therapeutic potential of liver X receptor beta (LXRβ) in treating depression and anxiety. This comprehensive analysis...
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DRUG MAY BOOST MOTIVATION FOR PEOPLE WITH DEPRESSION
SEPTEMBER 25TH, 2024POSTED BY EMORY UNIVERSITY(Credit: Getty Images) TAGS DEPRESSIONMOTIVATIONUNIVERSITY EMORY UNIVERSITYAn anti-inflammatory drug shows promise in boosting motivation for people with depression, a new study reveals. Motivational impairments are a core component of depression and have long been linked with poor treatment outcomes, diminished quality of life, and heightened suicide risk. Growing evidence suggests...
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Researchers find co-occurrence of depression and concussions amplify symptoms of both conditions
Graphical abstract. Credit: Brain Research (2024). DOI: 10.1016/j.brainres.2024.149200 Depression and sports-related concussion are neurological conditions that have many overlapping symptoms and uncertain recovery timelines. A study led by researchers at the Penn State Department of Kinesiology demonstrated that the co-occurrence of depression and concussion was associated with significantly worse symptoms for both conditions. Additionally, the researchers found that electrical signals in...
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All you need to know about agitated depression
Depression tends to involve feelings of hopelessness, sadness, or helplessness. However, some people also experience agitation, including symptoms of anxiety and restlessness. Agitated depression is not a medical term, but some people use it to describe the combination of anxiety and depression. Agitation can occur with major depression, bipolar disorder, and schizophrenia. In this article,...
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Psilocybin Bests SSRI for Major Depression in First Long-Term Comparison
Medscape Medical News > Conference News > ECNP 2024 Kate Johnson September 23, 2024 MILAN — Psilocybin leads to a better overall outcome in the treatment of moderate to severe major depressive disorder (MDD) than the selective serotonin reuptake inhibitor (SSRI) escitalopram, results of the first long-term comparison of the two treatments suggest. “This is...