Tag: <span>Depression</span>

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In patients with heart failure, anxiety and depression linked to worse outcomes

WOLTERS KLUWER HEALTH July 6, 2018 – Symptoms of depression and anxiety are present in about one-third of patients with heart failure – and these patients are at higher risk of progressive heart disease and other adverse outcomes, according to a review and update in the July/August issue of Harvard Review of Psychiatry. The journal is published...

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Scientists have discovered a new type of depression: Finding will pave the way for new treatments for 30% of patients who do not respond to drugs

Some mice with symptoms respond to drugs that act on ‘feel-good hormones’ Yet such medications have no effect on the mental states of other rodents Thought to be due to animals having different receptor levels for such hormones Findings may lead to new antidepressants that benefit more sufferers Around 7% of adults in the US...

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Mechanism controlling multiple sclerosis risk identified

While the DNA sequence remains the same throughout a person’s life, the expression of the encoded genes may change with time and contribute to disease development in genetically predisposed individuals. Researchers at Karolinska Institutet in Sweden have now discovered a new mechanism of a major risk gene for multiple sclerosis (MS) that triggers disease through so-called epigenetic...

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Study identifies a link between antidepressant treatment resistance and inflammation

Researchers at Emory University have found that depressed patients who have not responded to multiple antidepressants exhibit evidence of increased inflammation. Findings were recently published online in the journal, Psychoneuroendocrinology. Levels of inflammation can be easily measured by simple blood tests, like C-reactive protein (CRP), readily available in clinics and hospitals throughout the U.S. Credit: Emory University...

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The bacteria that could lead to a probiotic-based immunization for stress, anxiety and depression

Science has only just started to tease out a fascinating relationship between bacteria, inflammation and mood over the last few years. Not only are some conditions, such as depression, being hypothesized to be caused by brain inflammation, but it’s possible brain inflammation could be modulated by bacteria in our microbiome. Ambitious new research suggests a...

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Never ignore depression

(HealthDay)—Studies show that depression is underreported. People aren’t getting the help they need, sometimes because they don’t know the warning signs or where to turn, or are embarrassed because of the stigma that can still surround mental health issues. But the numbers are too great to ignore. Up to 26 percent of U.S. women and...

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Depression speeds up brain aging, find psychologists

Psychologists at the University of Sussex have found a link between depression and an acceleration of the rate at which the brain ages. Although scientists have previously reported that people with depression or anxiety have an increased risk of dementia in later life, this is the first study that provides comprehensive evidence for the effect...

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Brain stimulation reduces suicidal thinking in people with hard-to-treat depression

Findings indicate promising directions to prevent suicide across mental illnesses TORONTO, MAY 3, 2018 – A specific kind of brain stimulation is effective in reducing suicidal thinking in a significant portion of people with hard-to-treat depression, according to a new CAMH study published in The Journal of Clinical Psychiatry. Forty per cent of people in the study reported...

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Parkinson, Depression Meds Tied to Dementia Risk

Associations persisted up to 2 decades after exposure Long-term use of anticholinergic medications for Parkinson’s disease, bladder conditions, and depression was associated with an increased risk for dementia, a case-control study found. For drugs previously associated with delirium, the highest odds were seen with anticholinergic drugs for Parkinson’s (adjusted OR 1.29, 95% CI 1.11-1.50, P<0.01) and...

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Brain activity can predict success of depression treatment

McLean Hospital and Harvard Medical School researchers believe they have uncovered a method that could be useful in predicting a depressed patient’s treatment prognosis, prior to starting treatment. In the paper “Pretreatment Rostral Anterior Cingulate Cortex Activity in Relation to Symptom Improvement in Depression: A Randomized Clinical Trial,” currently available online and scheduled to appear...