By Bronwyn Thompson March 19, 2023 Scientists unlock more of the genetic code behind depression Depositphotos Depression is incredibly complex, highly individual and most often linked to a cache of other triggers and comorbidities. But in 2021, a look at 1.2 million people found 178 gene variants linked to major depressive disorder (MDD) and confirmed that our...
Tag: <span>Depression</span>
Progress in unlocking the brain’s ‘code’ for depression
by Elsevier Intracranial recording electrodes sample depression-relevant prefrontal regions. (A-C) Frontal views of the reconstructed cortical surface and stereo-EEG recording contacts for Patient 1, Patient 2 and Patient 3, respectively. Stereo-EEG contacts are colored according to the gray matter region sampled: green, anterior cingulate cortex (ACC); red, dorsolateral prefrontal cortex (dlPFC); blue, orbitofrontal cortex (OFC);...
Study finds protein in blood believed to be linked to depression
by Pasteur Institute A small group of neural stem cells isolated from mice and cultured in vitro observed under a confocal microscope. (LaminB1 in green, Sox2 in red) Credit: Perception and Memory Unit—Institut Pasteur The process of aging is often related to the onset of neurological symptoms such as cognitive decline, memory loss or mood...
Depression linked to immune response in some people
by University of Bristol Credit: Pixabay/CC0 Public Domain A link between depression and changes in counts of several types of immune cells in the blood has been revealed by researchers at the University of Bristol’s MRC Integrative Epidemiology Unit. These findings, published in Molecular Psychiatry, suggest that changes to different components of our immune system—both the innate and...
Depression common following a stroke impacting 1/3 of survivors
AMERICAN HEART ASSOCIATION DALLAS, Feb. 16, 2023 — According the American Stroke Association, a division of the American Heart Association, depression is a common experience for stroke survivors. A scientific statement from the Association indicates that about one-third of stroke survivors experience depression – compared to 5%–13% of adults without stroke. If left untreated, it...
Using deep learning to detect depression from speech
by Ingrid Fadelli, Medical Xpress Flowchart of the model’s front-end processing of voice signals. Credit: Tian, Zhu and Jing Artificial intelligence (AI) tools have achieved promising results on numerous tasks and could soon assist professionals in various settings. In recent years, computer scientists have been exploring the potential of these tools for detecting signs of...
DRUG COULD COUNTER INFLAMMATION LINKED TO DEPRESSION
Numerous labs across the world have shown that inflammation causes reduced motivation and anhedonia, a core symptom of depression, by affecting the brain’s reward pathways. Past research from the department of psychiatry and behavioral sciences at Emory University School of Medicine has linked the effects of inflammation on the brain to decreased release of dopamine, a chemical neurotransmitter that...
Researchers uncover a connection between multiple sclerosis lesions and depression
by Brigham and Women’s Hospital Credit: Pixabay/CC0 Public Domain Two major health conditions appear to share a connection. Multiple sclerosis (MS), a disease which eats away at the body’s central nervous system, affects millions of people globally and depression, a mood disorder with debilitating symptoms, affects hundreds of millions of people globally. Patients with MS are...
Doctors find mental health chatbots are effective in helping treat symptoms in people with depression
by Nanyang Technological University Credit: Pixabay/CC0 Public Domain Clinician scientists from Nanyang Technological University, Singapore (NTU Singapore) have found that mental health chatbots are able to effectively engage people with depression in empathetic conversations and assist in the treatment of their symptoms. Chatbots or conversational agents are computer programs that simulate human conversations. They are...
Faster Response to IV vs Intranasal Ketamine in Depression
Nancy A. Melville May 26, 2022 NEW ORLEANS – New research reveals that patients with treatment-resistant depression who were treated with repeated intravenous ketamine show no significant differences in achieving response or remission, compared with those receiving the intranasal formulation of the drug, esketamine – although fewer treatments appear necessary with the intravenous formulation. Dr Balwinder Singh...