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Designer probiotic treatment for cancer immunotherapy
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Designer probiotic treatment for cancer immunotherapy

by Columbia University School of Engineering and Applied Science Researchers at Columbia Engineering have engineered probiotics to safely deliver immunotherapies within tumors. These include nanobodies against two proven therapeutic targets—PD-L1 and CTLA-4. The drugs are continuously released by bacteria and continue to attack the tumor after just one dose, facilitating an immune response that ultimately...