Activating calcium channels leads to a deadly influx of calcium ions into tumor cellsPeer-Reviewed Publication WILEY Calcium ions are essential for cells, but can be toxic in higher concentrations. A team of researchers has now designed and prepared a combination drug that kills tumor cells by modulating the calcium influx into the cell. An external...
Tag: <span>destruction</span>
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In Krabbe disease, neurons may bring about their own destruction
by Public Library of Science University at Buffalo Dr. Daesung Shin (left) and a graduate student Jacob Favret (right) discuss neurodegeneration found in the neuron-specific Krabbe disease model. Credit: Daesung Shin (CC-BY 4.0, creativecommons.org/licenses/by/4.0/) The gene defect underlying Krabbe disease causes degeneration of neurons directly, independent of its effects on other cell types, according to a...
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New method targets disease-causing proteins for destruction
Scientists at the University of Wisconsin–Madison have developed a way to use a cell’s own recycling machinery to destroy disease-causing proteins, a technology that could produce entirely new kinds of drugs. Some cancers, for instance, are associated with abnormal proteins or an excess of normally harmless proteins. By eliminating them, researchers believe they can treat the underlying...
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New method targets disease-causing proteins for destruction
UNIVERSITY OF WISCONSIN-MADISON MADISON, Wis. — Scientists at the University of Wisconsin-Madison have developed a way to use a cell’s own recycling machinery to destroy disease-causing proteins, a technology that could produce entirely new kinds of drugs. Some cancers, for instance, are associated with abnormal proteins or an excess of normally harmless proteins. By eliminating...