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Scientists unravel life-saving effect of dexamethasone in COVID-19

NEWS RELEASE 3-JUL-2024 Study in “Cell” Peer-Reviewed PublicationDZNE – GERMAN CENTER FOR NEURODEGENERATIVE DISEASES Dexamethasone is one of the most important drugs in the treatment of severe COVID-19, but patients respond very differently to the therapy. Researchers at the German Center for Neurodegenerative Diseases (DZNE) and Charité – Universitätsmedizin Berlin have now discovered how the...

Dexamethasone no benefit in HIV-positive with tuberculous meningitis: Study
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Dexamethasone no benefit in HIV-positive with tuberculous meningitis: Study

by Elana Gotkine For HIV-positive adults with tuberculous meningitis, adjunctive dexamethasone does not confer a benefit with respect to survival, according to a study published in the Oct. 12 issue of the New England Journal of Medicine. Joseph Donovan, Ph.D., from the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam, and colleagues...

Dexamethasone enhances transgene expression
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Dexamethasone enhances transgene expression

by Mary Ann Liebert, Inc Figure 1. The long-term expression of hFIX in wild-type C57BL/6 mice pretreated with dexamethasone. (A) The schematic of the dexamethasone and AAV9/hFIX administrations and serum collection from blood. Dexamethasone (0.2 mg/mouse) or PBS was injected 2 h before 1 × 1010 vg of AAV9/hFIX vectors per mouse were administered through the retro-orbital vein. The...

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New discovery may change how dexamethasone is prescribed for some COVID-19 patients

DOE/ARGONNE NATIONAL LABORATORY Research has shown that dexamethasone, a widely available steroid, can significantly reduce the chance of death from COVID-19. However, because of the way dexamethasone is transmitted throughout the body, it may be less effective in patients with diabetes, according to new research performed at the Advanced Photon Source (APS), a U.S. Department...

COVID-19: Dexamethasone discovery carries treatment implications
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COVID-19: Dexamethasone discovery carries treatment implications

UNIVERSITY OF VIRGINIA HEALTH SYSTEM IMAGE: AN ARTIST’S RENDERING OF THE DEXAMETHASONE DISCOVERY, BY MARCIN MINOR.v A new discovery about how the body transports dexamethasone, a drug that can increase the survival chances of patients with severe COVID-19, suggests diabetes and other factors may reduce its potentially lifesaving effectiveness. Based on their findings, the researchers say doctors may...

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This revolutionary new coronavirus cure is already saving lives

A breakthrough coronavirus cure might soon be available, as researchers are studying a drug that could eliminate the virus, calm the immune response, and repair damaged tissue.  The drug is described in different ways: Medicinal signaling cells (MSCs), mesenchymal lineage adult stem cells, or adipose-tissue derived mesenchymal stromal cells (AT-MSC).  MSCs therapy proved to be very effective...