12 September 2024 By Max Kozlov Cellular measures of ageing changed more slowly in the liver, brain and other tissues of monkeys taking the drug metformin.Credit: Vachira Vachira/NurPhoto/Getty A low-cost diabetes drug slows ageing in male monkeys and is particularly effective at delaying the effects of ageing on the brain, finds a small study that...
September 10, 2024 by Bruno Geoffroy, University of Montreal Hospital Research Centre Graphical abstract. Credit: iScience (2024). DOI: 10.1016/j.isci.2024.110670Metformin, a drug used to treat type 2 diabetes, could help deplete the viral reservoir and eliminate it entirely in people living with HIV who receive antiretroviral therapy, Canadian researchers say in a new study. In 2021,...
September 4, 2024 by Steve Macfarlane, The Conversation Credit: Unsplash/CC0 Public DomainA Korean study published recently suggests that people with type 2 diabetes who are prescribed a particular class of drug might be at a significantly lower risk of dementia. The researchers compared the health outcomes of more than 110,000 people aged 40–69 with type...
by Wiley Credit: Pixabay/CC0 Public DomainResearch in animals has shown that the diabetes drug dulaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist may reduce symptoms of depression. A new study published in Brain and Behavior reveals the mechanisms that are likely involved. By conducting a range of tests in mice treated with and without dulaglutide,...
by Karolinska Institutet Credit: Pixabay/CC0 Public DomainOzempic and other GLP1 agonists are associated with a reduced risk of developing cirrhosis and liver cancer in people with type 2 diabetes and chronic liver disease, according to a nationwide study from Karolinska Institutet in Sweden published in the journal Gut. GLP1 agonists like Ozempic reduce blood sugar levels...
by British Medical Journal Credit: Pixabay/CC0 Public Domain The diabetes drug dulaglutide (Trulicity) may significantly lower a woman’s risk of substantial weight gain after she has given up smoking, finds a secondary analysis of clinical trial data, published in the open access journal BMJ Nutrition Prevention & Health. Women seem to be five times as likely...
Peer-Reviewed Publication CASE WESTERN RESERVE UNIVERSITY NATHAN BERGER CREDIT: CASE WESTERN RESERVE UNIVERSITY CLEVELAND—A groundbreaking study by researchers at Case Western Reserve University suggests a class of medications used to treat type 2 diabetes may also reduce the risk of colorectal cancer (CRC). The findings, published today (Dec. 7) in the journal JAMA Oncology, support...
by Justin Jackson, Medical Xpress Discovery and inhibition of a gut microbial–host isozyme to regulate host metabolism. Differences in the gut microbiota may explain why some individuals respond to antidiabetic DPP4 inhibitors but others do not. An activity-based enzyme activity screening system identified gut microbial DPP4 isozymes that can decrease active GLP-1 but cannot be...
Megan Brooks February 16, 2023 Treatment with the thiazolidinedione pioglitazone may offer the greatest protection against dementia for older adults with newly diagnosed type 2 diabetes mellitus (T2DM) who have a history of stroke or ischemic heart disease, new research suggests. Overall, in a large cohort study from Korea, patients who took pioglitazone were 16% less likely to develop dementia over an average of...
Carolyn Crist March 09, 2023 Metformin appears to play a role in preventing long COVID when taken early during a COVID-19 infection, according to a new preprint study from The Lancet. The preprint hasn’t yet been peer-reviewed or published in a journal. In particular, metformin led to a 42% drop in long COVID among people who had a mild to...
