by University of Geneva Human pancreatic islet cells with compromised clocks bear decreased membrane lipid fluidity, as compared to the islet cells with functional clocks © 2022. Petrenko et al. (2022) Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets. Credit: PLOS Biology (2022). DOI: 10.1371/journal.pbio.3001725 Like all living beings, human...
by Nagoya University Credit: Unsplash/CC0 Public Domain A research group at Nagoya University in Japan has discovered a new treatment for type 1 diabetes that uses leptin, a hormone secreted by fat cells. Treating mice models of insulin-dependent diabetes mellitus (a condition found primarily in type 1 diabetes) with a combination of leptin and a...
Among patients with type 1 diabetes, percentage of time in the target glucose range is increased with the use of an open-source automated insulin delivery (AID) system, according to a study published in the Sept. 8 issue of the New England Journal of Medicine. Mercedes J. Burnside, M.B., Ch.B., from the University of Otago in New...
by Nemours Children’s Health System Credit: Pixabay/CC0 Public Domain Tight control of blood sugar in teens with Type 1 diabetes may help reduce the disease’s damaging effects on the brain, effects which have been shown even in younger children, according to a study published online today in Nature Communications. The findings indicate that better glucose control can...
Reviewed by Emily Henderson, B.Sc. Sep 1 2022 New research confirms for the first time that ethnicity is a risk factor for developing kidney disease in people with Type 1 diabetes. The study is one of the largest of its type and is published today in Diabetes Care by researchers from King’s College London. The findings also show...
by Science China Press (a) Mean HbA1c during lead-in and 26-week treatment. Data are mean at screening and LSM (± SE) for all other time points. Noninferiority of URLi versus insulin lispro was shown in change of HbA1c from baseline to week 26. (b) LSM post-prandial glucose excursions at weeks 26 during mixed-meal tolerance tests....
by Birgit Niesing, Deutsches Zentrum für Diabetesforschung GLP-1RA/tesaglitazar in obese GLP-1R knockout mice. a–n, Body weight (a,h), change in fat and lean tissue mass (b,c,i,j), cumulative food intake (d,k), blood glucose (e,l) and i.p. GTT (f,m) in 36-week-old male DIO wildtype (WT) (a–g) or GLP-1R knockout (KO) mice (h–n) treated for 6 days with either vehicle...
by University of Utah Health Sciences Pedigree of the family enriched for diabetes and end-stage renal disease and identification of the ADIPOQ mutation. a The family pedigree, status of diabetes (shaded) and end-stage renal disease (ESRD; red outline), and the ADIPOQ mutation (p.Gly93GlufsTer73). Carriers of the wild-type ADIPOQ insertion (I) or mutated ADIPOQ deletion (D; red) are indicated. b The structure of the wild-type (top) and...
by British Medical Journal Credit: CC0 Public Domain An artificial intelligence (AI) algorithm, derived from the features of individual heartbeats recorded on an ECG (electrocardiogram), can accurately predict diabetes and pre-diabetes, suggests preliminary research published in the online journal BMJ Innovations. If validated in larger studies, the approach could be used to screen for the disease in...
By Rich Haridy August 07, 2022 A new study proposes a blood biomarker could be a useful way to detect patients at risk of either developing diabetes or experiencing severe cancer outcomes Depositphotos A new study has found people with elevated blood levels of a protein called prostasin face a significantly higher risk of developing...
