by Zehan Yu, Duke-NUS Medical School Mucosal vaccination protects hamsters from SARS-CoV-2-induced clinical disease. (a) Diagram of the experimental design where hamsters were vaccinated with S-RBD and M7 via various routes using a prime (day 0) and boost (day 14). Credit: eBioMedicine (2023). DOI: 10.1016/j.ebiom.2023.104924A team of scientists, led by Duke-NUS Medical School, has discovered a...
Tag: <span>discovery</span>
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Research makes important discovery about pulmonary sequelae after COVID-19 infection
by MELISA Institute timsTOF Pro 2 mass spectrometer (Bruker Daltonics), nanoElute (Bruker Daltonics) and Evosep ONE (Evosep Biosystems) chromatographs, in the MELISA Institute laboratory. Credit: MELISA InstituteA collaborative study sought to identify the sequelae associated with long-term pulmonary dysfunction (L-PDD) in patients with COVID-19. The study was published in Frontiers in Medicine. The research was...
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Researchers discover a mechanism that controls the identity of stem cells
by University of California, Irvine Credit: Molecular Cell (2023). DOI: 10.1016/j.molcel.2023.10.036 Researchers at the University of California, Irvine, discovered a mechanism that controls the identity of stem cells. When this mechanism fails, embryonic stem cells revert back in time and become totipotent. When a cell becomes totipotent, this rare change enables the cells to differentiate into...
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DISCOVERY GETS US CLOSER TO ‘MUSCLE IN A DISH’
NOVEMBER 14TH, 2023POSTED BY UC IRVINE One disorder the Hicks lab hopes to treat with their lab-grown muscle progenitors is tears to the rotator cuff muscles, which affects up to 30% of people over the age of 65. (Credit: Getty Images) Researchers have identified a gene expressed during regeneration that is critical for muscle repair. The key...
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How Botox enters brain cells, a discovery that could save lives
by University of Queensland Credit: The EMBO Journal (2023). DOI: 10.15252/embj.2022112095 Researchers from The University of Queensland have determined how Botox—a drug made from a deadly biological substance—enters brain cells. Professor Frederic Meunier and Dr. Merja Joensuu at UQ’s Queensland Brain Institute have discovered the specific molecular mechanism by which the highly deadly Botulinum neurotoxin type-A, more widely...
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Discovery of a potential therapeutic target for ALS
UNIVERSITY OF MALTA IMAGE: STUDY FIRST AUTHOR DR. REBECCA BORG AND LEAD INVESTIGATOR PROF. RUBEN CAUCHI HOLDING A VIAL WITH FRUIT FLIES (PHOTO BY CHRIS SANT FOURNIER). CREDIT: CHRIS SANT FOURNIER University of Malta researchers have discovered a potential new drug target for amyotrophic lateral sclerosis (ALS), according to a new study published in the Neurobiology of Aging journal....
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From Droplet to Discovery
Stem cells overflow with potential. Their ability to become other cell types is crucial to our bodies during development and throughout life. But this potential can be our downfall if it goes wrong, turning some of our most useful cells into malignant cancers. While investigating a pathway involved in stem cell differentiation, researchers at UC Santa Barbara found...
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Researchers discover new genetic eye disease
by National Institutes of Health Retinal images of a patient with a TIMP3 mutation causing atypical symptoms. While there is visible damage in the retina (dark circles), there is no CNV present. Credit: NEI Researchers from the National Eye Institute (NEI) have identified a new disease that affects the macula, a small part of the light-sensing...
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Discovery could lead to better cancer immunotherapy
Washington State University Credit: Unsplash/CC0 Public Domain A type of white blood cell previously known only as a helper in the immune system appears also to be the instigator of the body’s defenses against cancerous tumors. The discovery could lead to more effective cancer immunotherapy, a promising treatment which uses the body’s own immune system,...
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Discovery could pave way for new lung treatment
ANGLIA RUSKIN UNIVERSITY Scientists have discovered a new family of helpful proteins in the lung, with the finding potentially paving the way for a new course of treatment for patients with respiratory failure. Researchers from Anglia Ruskin University (ARU), alongside colleagues from Brown University and the Providence Veterans Affairs Medical Center in Rhode Island, US,...