UNIVERSITY OF EDINBURGH Scientists have long sought to find out how some diseases can have symptoms restricted to just one tissue when they are caused by a single faulty protein found throughout the body. Familial Partial Lipodystrophy type 2 (FPLD2) is a rare disorder causing diabetes, loss of fat in the arms and legs, and...
Tag: <span>discovery</span>
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Breast cancer discovery could help stop disease’s deadly spread
UNIVERSITY OF VIRGINIA HEALTH SYSTEM IMAGE: UVA’S SANCHITA BHATNAGAR, PHD, FOUND THAT THE BREAST CANCER ONCOGENE TRIM37 NOT ONLY CAUSES TRIPLE NEGATIVE BREAST CANCER TO SPREAD BUT ALSO MAKES IT RESISTANT TO CHEMOTHERAPY. University of Virginia Cancer Center researchers have identified a gene responsible for the spread of triple-negative breast cancer to other parts of the body...
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Discovery holds potential for reversing vision loss
by Oklahoma Medical Research Foundation An Oklahoma Medical Research Foundation discovery could pave the way for therapies to reverse vision loss common in premature infants and adults. In a new study appearing in the Proceedings of the National Academy of Sciences, OMRF scientists have identified a compound that could give birth to therapies for a host of eye diseases that...
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Failed Alzheimer’s drugs given new life after human gene discovery
By Rich Haridy August 19, 2020 A new study is questioning whether potential Alzheimer’s treatments previously found to be ineffective in human trials should be re-examined, after the discovery of a specific gene that can inhibit a therapy’s efficacy is only present in 75 percent of people. The long-standing cholinergic hypothesis for Alzheimer’s disease suggests...
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Scientists discover a novel neuroimmune pathway
by ShanghaiTech University Research carried out collaboratively by Professors Qi Hai and Zhong Yi from Tsinghua University and Professor Hu Ji from the School of Life Science and Technology (SLST) of ShanghaiTech University was published in a Nature article titled “Brain control of humoral immune responses amenable to behavioral modulation.” The researchers identify a specific...
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New discovery explains how the prostate gland regenerates itself
by Memorial Sloan Kettering Cancer Center Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia The standard treatment for men with advanced prostate cancer is androgen-deprivation therapy. Androgens are hormones that fuel prostate cell growth; removing them with either drugs or surgery causes the prostate gland to shrink by 90%....
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Scientific discovery may lead to a treatment for lupus
By Dr. Liji Thomas, MD When there is an excessive number or hyperactivation of immune cells, very high levels of proteins known as cytokines are released, resulting in a cytokine storm that causes severe and often irreversible tissue damage. This accounts for the crippling nature of many autoimmune disorders such as lupus. Now, an international team of...