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Loop Diuretics: Getting the Dose Right

Tom G. Bartol, MN, NP DISCLOSURES July 10, 2019 Loop diuretics are widely used in the management of edema and heart failure. They are also widely misunderstood. The reason is this: Loop diuretics are often prescribed in a dose-dependent strategy. Looking for gentle diuresis? Prescribe a low dose. For a more dramatic response, use a higher dose. But loop diuretics (eg, furosemide, torsemide, bumetanide) don’t work that way. Loop diuretics are “all-or-none” drugs; they...