by Bob Yirka, Medical Xpress FIG. 1. CGI− gene misexpression and nuclear architecture disruption in aged kidneys. (A) Schematic showing dual mode gene regulation mediated by CGI. Only CGI− genes form lamina-associated heterochromatin, which is disrupted during aging (see also fig. S1A). (B) Example comparison of CGI+ and CGI− gene expression in kidney from a...
