by Jade Boyd, Rice University A low-cost, point-of-care DNA test for HPV infections that was invented at Rice University delivers results in 45 minutes and requires just two pieces of equipment, a small centrifuge (not shown) that costs about $500 and NATflow, a purpose-built, dual-chamber heater that uses disposable cartridges to prevent false positives arising from...
by University of Cambridge Credit: Pixabay/CC0 Public Domain A study of the DNA of more than 55,000 people worldwide has shed light on how we maintain healthy blood sugar levels after we have eaten, with implications for our understanding of how the process goes wrong in type 2 diabetes. The findings, published in Nature Genetics, could help...
THE HOSPITAL FOR SICK CHILDREN Scientists at The Hospital for Sick Children (SickKids) are delving deep into the non-coding genome to unravel the complex genetics that underlie blood pressure regulation and hypertension (high blood pressure) – the leading cause of cardiovascular disease affecting 1.25 billion people worldwide. While the human genome comprises coding and non-coding...
UNIVERSITY OF CALIFORNIA – SAN DIEGO IMAGE: AN ARTISTIC RENDERING OF THE CONCEPT OF DNA DAMAGE AND REPAIR. NUMEROUS DISEASES ARE LINKED TO OR CAUSED BY ALTERATIONS THAT AFFECT GENOMIC INTEGRITY AND THE ABILITY OF CELLS TO FUNCTION AND DIVIDE NORMALLY. A PROCESS CALLED DNA DAMAGE RESPONSE HAS EVOLVED TO REPAIR ERRORS AND MUTATIONS. RESEARCHERS...
by NYU Langone Health The study enzyme RNAseHII repairs DNA by riding along on the enzyme that reads the genetic code, RNA polymerase, and cutting out (see scissors) misplaced code letters when it “sees” them in bacterial genetic material. Credit: Cell Press A new study adds to an emerging, radically new picture of how bacterial cells...
by Johns Hopkins University School of Medicine In a study of 17 people from five families, Johns Hopkins Medicine researchers say they found that ultra-lengthy DNA endcaps called telomeres fail to provide the longevity presumed for such people. Instead, people with long telomeres tend to develop a range of benign and cancerous tumors, as well as the...
by Virginia Commonwealth University Credit: Pixabay/CC0 Public Domain An international research team led by investigators at Virginia Commonwealth University has identified for the first time markers that may indicate early in life if a person has susceptibility to schizophrenia. The ability to predict the risk of developing schizophrenia later in life may allow early detection and intervention, which...
by The University of Hong Kong Knockout of ANKLE1 induces excessive accumulation of cytosolic DNA, leading to activation of immune responses. Credit: Dr Gary Ying Wai Chan and Dr Huadong Jiang A research team led by Dr. Gary Ying Wai Chan from the School of Biological Sciences at The University of Hong Kong (HKU), has revealed...
By Bronwyn Thompson March 19, 2023 Scientists unlock more of the genetic code behind depression Depositphotos Depression is incredibly complex, highly individual and most often linked to a cache of other triggers and comorbidities. But in 2021, a look at 1.2 million people found 178 gene variants linked to major depressive disorder (MDD) and confirmed that our...
It is known that toxins in tobacco smoke can change our DNA – but where exactly in the genome they do this has been a mystery. A new approach developed by researchers at ETH Zurich now brings light into the darkness. In the future, this could make it easier than ever to determine the safety of many...
