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Extra virgin olive oil may delay cognitive decline in Down syndrome

Researchers working with the Alzheimer’s Center at Temple (ACT) recently investigated the effect of extra virgin olive oil (EVOO) on brain health and memory to determine if consumption of extra virgin olive oil, the main component of the Mediterranean diet, can delay cognitive decline in people with Down syndrome (DS). DS is the most common...

Clinical trial shows JAK inhibitor improves multiple autoimmune conditions in patients with Down syndrome
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Clinical trial shows JAK inhibitor improves multiple autoimmune conditions in patients with Down syndrome

August 13, 2024 by CU Anschutz Medical Campus Acutal results of clinical trial participant with alopecia areata after four months of treament. Credit: Linda Crnic Institute for Down Syndrome Multi-organ autoimmunity and widespread autoantibody production in Down syndrome.A new study published in eLife by researchers from the Linda Crnic Institute for Down Syndrome (Crnic Institute)...

Alzheimer’s Starts Earlier and Progresses Faster in People With Down Syndrome
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Alzheimer’s Starts Earlier and Progresses Faster in People With Down Syndrome

A new study revealed that Alzheimer’s disease starts earlier and progresses faster in people with Down syndrome.Original story from Washington University School of Medicine in St Louis A scientist in a white lab coat helps a person with Down syndrome into a brain scan machine.Washington University senior clinical research coordinator Brittany Nelson (front) helps study...

Weight loss may be early predictor of Alzheimer’s disease in those with Down syndrome
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Weight loss may be early predictor of Alzheimer’s disease in those with Down syndrome

by Charlene N. Rivera-Bonet, University of Wisconsin-Madison Credit: Unsplash/CC0 Public Domain Unintentional weight loss in people with Down syndrome may predict the onset of Alzheimer’s disease long before typical cognitive symptoms like memory loss and dementia are apparent. As many as 90% of people with Down syndrome experience Alzheimer’s symptoms by the time they are...

Down syndrome, like Alzheimer’s, is a double-prion disorder
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Down syndrome, like Alzheimer’s, is a double-prion disorder

by University of California, San Francisco PET scan of a human brain with Alzheimer’s disease. Credit: public domain The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer’s disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. A new study from researchers at...

A therapy found to improve cognitive function in patients with Down syndrome
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A therapy found to improve cognitive function in patients with Down syndrome

by Institut National de la Sante et de la Recherche Medicale Credit: CC0 Public Domain An Inserm team at the Lille Neuroscience & Cognition laboratory (Inserm/Université de Lille, Lille University Hospital) has joined forces with its counterparts at Lausanne University Hospital (CHUV) to test the efficacy of GnRH injection therapy in order to improve the...

Blood test detects Alzheimer’s in people with Down syndrome
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Blood test detects Alzheimer’s in people with Down syndrome

by Lund University Credit: Unsplash/CC0 Public Domain Around 80% of people with Down syndrome develop Alzheimer’s disease, often when they are between 40 and 50 years old. A study led by Lund University in Sweden has shown that a simple blood test can detect Alzheimer’s disease in people with Down syndrome with a high degree...

Earlier intervention in Down syndrome may be possible, study finds
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Earlier intervention in Down syndrome may be possible, study finds

by CU Anschutz Medical Campus Credit: Unsplash/CC0 Public Domain Could oxidative stress, a condition known to cause inflammation and cellular breakdown, impact the trajectory of Down syndrome cell development? Researchers at the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences recently published findings that examine the early stages of neurodevelopment. What they found...

Common antiretroviral drug improves cognition in mouse model of Down syndrome
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Common antiretroviral drug improves cognition in mouse model of Down syndrome

by Center for Genomic Regulation  Antiretroviral medication lamivudine pictured at the IrsiCaixa AIDS research institute in Barcelona. Credit: IrsiCaixa Lamivudine, a commonly-used antiretroviral drug for treating HIV, improves cognition in a mouse model of Down syndrome, according to the findings of a joint new study by researchers at the Centre for Genomic Regulation (CRG) and...

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Clues from Down syndrome hint at new Alzheimer’s finding

For a long time, common diseases (think Alzheimer’s, cancer and other ailments) were thought to arise mostly from molecular or genetic mishaps. But scientists are finding that there seems to be increased involvement of an unexpected culprit: stem cells. Nine years ago, Stanford oncologist Michael Clarke, MD, made a connection between stem cells and Down syndrome: He...

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