A new study revealed that Alzheimer’s disease starts earlier and progresses faster in people with Down syndrome.Original story from Washington University School of Medicine in St Louis A scientist in a white lab coat helps a person with Down syndrome into a brain scan machine.Washington University senior clinical research coordinator Brittany Nelson (front) helps study...
by Charlene N. Rivera-Bonet, University of Wisconsin-Madison Credit: Unsplash/CC0 Public Domain Unintentional weight loss in people with Down syndrome may predict the onset of Alzheimer’s disease long before typical cognitive symptoms like memory loss and dementia are apparent. As many as 90% of people with Down syndrome experience Alzheimer’s symptoms by the time they are...
by University of California, San Francisco PET scan of a human brain with Alzheimer’s disease. Credit: public domain The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer’s disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. A new study from researchers at...
by Institut National de la Sante et de la Recherche Medicale Credit: CC0 Public Domain An Inserm team at the Lille Neuroscience & Cognition laboratory (Inserm/Université de Lille, Lille University Hospital) has joined forces with its counterparts at Lausanne University Hospital (CHUV) to test the efficacy of GnRH injection therapy in order to improve the...
by Lund University Credit: Unsplash/CC0 Public Domain Around 80% of people with Down syndrome develop Alzheimer’s disease, often when they are between 40 and 50 years old. A study led by Lund University in Sweden has shown that a simple blood test can detect Alzheimer’s disease in people with Down syndrome with a high degree...
by CU Anschutz Medical Campus Credit: Unsplash/CC0 Public Domain Could oxidative stress, a condition known to cause inflammation and cellular breakdown, impact the trajectory of Down syndrome cell development? Researchers at the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences recently published findings that examine the early stages of neurodevelopment. What they found...
by Center for Genomic Regulation Antiretroviral medication lamivudine pictured at the IrsiCaixa AIDS research institute in Barcelona. Credit: IrsiCaixa Lamivudine, a commonly-used antiretroviral drug for treating HIV, improves cognition in a mouse model of Down syndrome, according to the findings of a joint new study by researchers at the Centre for Genomic Regulation (CRG) and...
For a long time, common diseases (think Alzheimer’s, cancer and other ailments) were thought to arise mostly from molecular or genetic mishaps. But scientists are finding that there seems to be increased involvement of an unexpected culprit: stem cells. Nine years ago, Stanford oncologist Michael Clarke, MD, made a connection between stem cells and Down syndrome: He...
TEMPLE UNIVERSITY HEALTH SYSTEM (Philadelphia, PA) – Life expectancy for individuals with Down syndrome has grown in recent decades, thanks in large part to progress in patient care and treatment. But with survival into the fifth and sixth decades of life now possible, increasing numbers of these individuals are affected by conditions linked to aging,...
by Kyoto University Karyotype analysis of the iPSC clones. Credit: DOI: 10.1038/s41598-021-96697-7 Down syndrome is mostly known for the learning disabilities it causes, but patients typically suffer from a wide number of ailments. One is the early onset of Alzheimer’s disease. Using iPS cells from Down syndrome patients, a new study by CiRA researchers suggests that the molecular...
