JUNE 3, 2024 by Virginia Commonwealth University DAGLβ regulation of lipid signaling. Credit: Proceedings of the National Academy of Sciences (2023). DOI: 10.1073/pnas.2304900120A team of researchers from Virginia Commonwealth University, the University of Texas at Austin and the University of Virginia have made progress toward developing a drug candidate for treating chronic pain more safely....
UPPSALA UNIVERSITY IMAGE: MIA PHILLIPSON, PROFESSOR AT THE DEPARTMENT OF MEDICAL CELL BIOLOGY AT UPPSALA UNIVERSITY. CREDIT: MIKAEL WALLERSTEDT omplicated, hard-to-heal wounds are a growing medical problem and there are currently only two drugs approved with proven efficacy. In a new study on humans, researchers at Uppsala University show that treatment with a specific type...
by City University of Hong Kong D4 treatment decreases the proliferation and activation of astrocytes in two different brain regions. Pilocarpine was injected into the mice intraperitoneally to induce seizures. Seven days after pilocarpine-induced seizures, the researchers observed a chronic elevation in the number of astrocytes (marked by GFAP staining in red; all cell nuclei...
AMERICAN CHEMICAL SOCIETY Urinary tract infections are common, yet are increasingly tough to treat because the bacteria that cause them are becoming resistant to many antibiotics. Now, in ACS Central Science, researchers report a new molecule that inhibits drug-resistant bacteria in lab experiments, as well as in mice with pneumonia and urinary tract infections. The researchers...
by Okayama University The new synthesis technique offers higher yields than convential methods of synthesis and also succeeded in reducing the use of organic solvents, thus making the overall process more sustainable. Credit: Hiroki Kakuta Inflammatory bowel disease (IBD), characterized by a chronic inflammation of the digestive tract, is currently treated with steroids and antibody...
by University of Oulu Credit: University of Oulu / Mikko Törmänen A potential new drug candidate developed by researchers at the University of Oulu, Finland, has been granted a patent in the United States. The drug is a small molecular chemical compound that is especially suited for cancer treatment. The research group, led by professor...
Designer peptide could become effective in reducing damage caused by COVID-19 infections UNIVERSITY OF TORONTO – FACULTY OF DENTISTRY TORONTO, ON (June 30, 2020) — A collaboration between the University of Toronto’s Faculty of Dentistry and the National Jewish Health in Denver — the top-ranked respiratory research hospital in the U.S. — has yielded a...
by Rensselaer Polytechnic Institute A newly identified compound is a promising candidate for inhibiting the production of amyloids, the abnormal proteins that form toxic clumps, called fibrils, inside the brains of patients with Alzheimer’s disease. As published today in the Royal Society of Chemistry’s Chemical Communications, the compound—known as “C1″—uses a novel mechanism to efficiently...
