Waldenström macroglobulinemia (WM), a rare form of lymphoma, does not have any known cure and only one FDA-approved treatment making it challenging to treat patients. Researchers at the University of New Hampshire took the novel approach of targeting specific cell proteins that control DNA information using inhibitors, or drugs, that were effective in reducing the growth of...
by European Organization for Research and Treatment of Cancer Malignant tumors of the peripheral nerve are rare but aggressive and very difficult to treat successfully. Now, researchers in the U.S. have shown that a combination of two types of anti-cancer drugs, MEK and SHP2 inhibitors, is effective in targeting the mechanism that drives the cancer’s growth. Although...
People have searched for sex differences in human brains since at least the 19th century, when scientist Samuel George Morton poured seeds and lead shot into human skulls to measure their volumes. Gustave Le Bon found men’s brains are usually larger than women’s, which prompted Alexander Bains and George Romanes to argue this size difference...
UNIVERSITY OF WARWICK THE BALDS EYESALVE MIXTURE IN THE LAB.view more CREDIT: UNIVERSITY OF WARWICK Antibiotic resistance is an increasing battle for scientists to overcome, as more antimicrobials are urgently needed to treat biofilm-associated infections. However scientists from the School of Life Sciences at the University of Warwick say research into natural antimicrobials could provide...
According to a BBC report, the UK has authorized the use of the anti-viral drug Remdesivir in treating patients with the novel coronavirus as experts have discovered that the drug could shorten the recovery time of infected individuals. At last a breakthrough! Looking forward to discussing use of #REMDESIVIR against #COVID__19 with @mrdanwalker & #louiseminchin...
Scientists are locked in a high-stakes race against bacterial evolution, racing against adversaries that can spawn a new generation in less time than it takes to wash a load of laundry. New strains of antibiotic-resistant pathogens emerge faster than we can develop drugs to fight them, and experts warn that there may come a day...
If the fit is right, face masks made of a combination of high thread-count cotton and natural silk fabric or a chiffon weave can effectively filter out aerosol particles, researchers report. In the wake of the COVID-19 pandemic, the US Centers for Disease Control and Prevention recommends that people wear masks in public. Because N95...
NEW YORK (Reuters Health) – The single-tablet combination of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) is effective for long-term viral suppression in previously untreated patients with HIV-1 infection, according to 96-week results from the AMBER trial. Week 48 primary analyses of the AMBER trial and the companion EMERALD trial showed that D/C/F/TAF had high, noninferior antiviral efficacy with...
Scientists have identified the binding pocket for molecules that can stabilize a key braking mechanism in cancer — opening the door to the development of drugs that target it. A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds...
by Anne Trafton, Massachusetts Institute of Technology People with autism often experience hypersensitivity to noise and other sensory input. MIT neuroscientists have now identified two brain circuits that help tune out distracting sensory information, and they have found a way to reverse noise hypersensitivity in mice by boosting the activity of those circuits. One of the circuits the researchers identified is involved in filtering noise, while the...
