September 25, 2024 by Columbia University Tumors in a section of untreated muscle invasive bladder cancer (left) vs. section treated with Rosiglitazone and Trametinib showing 91% fewer tumors (right). Credit: Columbia UniversityA new study in mice by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) has identified a promising drug combination for the treatment...
Tag: <span>Drug combo</span>
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Machine learning uncovers the best drug combos to prevent COVID recurrence
by Jules Bernstein, University of California – Riverside Credit: Pixabay/CC0 Public Domain A groundbreaking machine-learning study has unmasked the best drug combinations to prevent COVID-19 from coming back after an initial infection. It turns out these combos are not the same for every patient. Using real-world data from a hospital in China, the UC Riverside-led study...
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Drug combo ups progression-free survival for metastatic prostate cancer
by Elana Gotkine For patients with metastatic castration-resistant prostate cancer (mCRPC), talazoparib plus enzalutamide results in improvement in radiographic progression-free survival (rPFS), according to a study published online June 4 in The Lancet to coincide with the annual meeting of the American Society of Clinical Oncology, held from June 2 to 6 in Chicago. Neeraj Agarwal, M.D., from the...
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Drug Combo Promising in Vascular Cognitive Impairment: LACI-2
Sue Hughes February 13, 2023 A combination of two drugs has shown promising results, including a reduction in cognitive impairment in patients who have had a lacunar stroke, and is seen as a new therapeutic approach for patients with cerebral small vessel disease. The drugs — isosorbide mononitrate and cilostazol — stabilize endothelial function, which is a new therapeutic target for patients...
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2-DRUG COMBO SHRINKS BREAST CANCER TUMORS
Their findings could lead to the development of a new first line targeted therapy for the treatment of triple negative breast cancer (TNBC), with the prospect of rapidly transitioning to clinical trials in humans. Breast cancer is the leading cause of cancer death in women around the world, responsible for 1,700 deaths every day. Although...
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UniSA research uncovers treatment combo that sees smokers six times more likely to quit
New research led by University of South Australia has found that smokers who receive the medication varenicline tartrate combined with Quitline counselling following a period of hospitalisation due to a tobacco-related illness are six times more likely to quit smoking than those who attempt to stop without support. The world-first study led by UniSA’s Associate...
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Drug combo reverses arthritis in rats
People with osteoarthritis, or “wear and tear” arthritis, have limited treatment options: pain relievers or joint replacement surgery. Now, Salk researchers have discovered that a powerful combination of two experimental drugs reverses the cellular and molecular signs of osteoarthritis in rats as well as in isolated human cartilage cells. Their results were published in the...
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Three-drug combo improves lung function in most common genetic form of cystic fibrosis
DALLAS – Oct. 31, 2019 – A phase three clinical trial that UT Southwestern participated in determined that a three-drug combination improved lung function and reduced symptoms in cystic fibrosis (CF) patients who have a single copy of the most common genetic mutation for the disease. Earlier this month, the Food and Drug Administration approved...