IOS PRESS IMAGE: TIMELINE OF SOME OF THE KEY EVENTS ESTABLISHING ANTICIPATION AS A GENUINE BIOLOGICAL PHENOMENON AND SOMATIC EXPANSION AS CONTRIBUTING TOWARD HUNTINGTON’S DISEASE PATHOLOGY. CREDIT: : DARREN G. MONCKTON IN “THE CONTRIBUTION OF SOMATIC EXPANSION OF THE CAG REPEAT TO SYMPTOMATIC DEVELOPMENT IN HUNTINGTON’S DISEASE: A HISTORICAL PERSPECTIVE, ” JOURNAL OF HUNTINGTON’S DISEASE...
by University of Toronto What started as a hallway conversation between colleagues is now an “engine for the discovery of new therapeutic targets in cells” thanks to Medicine by Design, says Shana Kelley, a University Professor in the Leslie Dan Faculty of Pharmacy at the University of Toronto. Kelley’s lab was developing a portable, chip-like...
By DAMIAN GARDE @damiangarde Thirty patients have died after taking a Vertex (VRTX) Pharmaceuticals treatment for cystic fibrosis, according to a government database, news that sent the company’s share price down as much as 4% on Wednesday morning. The deaths, reported to the Food and Drug Administration’s database of side effects, relate to patients who...
SLAS (SOCIETY FOR LABORATORY AUTOMATION AND SCREENING) A new special issue of SLAS Discovery reflects examples of the recent groundswell of creative new applications for high-throughput flow cytometry (HTFC) in drug discovery. IMAGE: HIGH-THROUGHPUT FLOW CYTOMETRY IN DRUG DISCOVERY. Led by guest editors Mei Ding, Ph.D. (AstraZeneca) and Bruce S. Edwards, Ph.D. (University of New Mexico),...
Fighting cancer means killing cancer cells. However, oncologists know that it’s also important to halt the movement of cancer cells before they spread throughout the body. New research, published today in the journal Nature Communications, shows that it may be possible to freeze cancer cells and kill them where they stand. Ryan Gordon, Ph.D., and Raymond Bergan,...
LA JOLLA, CA – January 19, 2017 – A team led by scientists at The Scripps Research Institute (TSRI) has developed a versatile new method that should enhance the discovery of new drugs and the study of proteins. The new method enables researchers to quickly find small molecules that bind to hundreds of thousands of...
