Written by Niousha Nader, PharmD, BCCCP | Reviewed by Soojin Jun, PharmD Published on April 17, 2024 Key takeaways: With age, you may find that you’re taking more prescription and over-the-counter medications to manage health conditions. This can put you at a higher risk for harmful side effects and risky drug interactions.Some drug interactions can...
by The Korea Advanced Institute of Science and Technology (KAIST) Results of drug interaction prediction between Paxlovid ingredients and representative approved drugs using DeepDDI2 (670KB) . Credit: The Korea Advanced Institute of Science and Technology (KAIST) Professor Sang Yup Lee’s research team in KAIST’s Department of Biochemical Engineering has developed an advanced AI-based drug interaction prediction technology...
by University of Bonn The figure shows an overview of the potential protein-protein interaction patterns at reduced (left) and increased (right) protein concentrations in the spleen of Duchenne mice. Credit: Maynooth University Duchenne muscular dystrophy (DMD) is the most common muscle disease in children and is passed on by X-linked recessive inheritance. Characteristic is a...
Reviewed by James Ives, M.Psych. (Editor) COVID-19 may increase the risk of blot cots in women who are pregnant or taking estrogen with birth control or hormone replacement therapy, according to a new manuscript published in the Endocrine Society’s journal, Endocrinology. One of the many complications of COVID-19 is the formation of blood clots in...
TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE DAMAGED MITOCHONDRIA ARE SELECTIVELY ELIMINATED VIA AUTOPHAGY CALLED MITOPHAGY. IN MAMMALIAN CELLS, UBIQUITIN CHAINS ON THE DAMAGED MITOCHONDRIA PLAY CRITICAL ROLES TO INDUCE MITOPHAGY. Researchers at TMIMS have revealed that PINK1 (a serine/threonine kinase) and Parkin (a ubiquitin ligating enzyme: E3) work together to ubiquitylate the outer membrane proteins...
by Johannes Angerer, Medical University of Vienna As the population ages, the prevalence of chronic disease increases. As a result, more drugs are prescribed. Around 25% of the population aged 65+ are affected by so-called “polypharmacy,” i.e., they regularly take at least five drugs. This results in an increased risk for drug interactions and adverse...
CORVALLIS, Ore. – Hop-based dietary supplements that many women use to ease the night sweats and hot flashes commonly reported during menopause aren’t likely to cause drug interactions, new research from Oregon State University’s Linus Pauling Institute and College of Pharmacy shows. The findings are important because while hormone replacement therapy remains the standard of...
Complications often go undetected but can contribute to misuse and overdose, according to The Journal of the American Osteopathic Association AMERICAN OSTEOPATHIC ASSOCIATION CHICAGO–December 10, 2019– Patients who do not disclose use of other medications are at higher risk of adverse drug interactions and addiction, according to new research in The Journal of the American...
OCTOBER 17TH, 2019POSTED BY MATT SWAYNE-PENN STATE A machine learning system may be able to warn doctors and patients about possible negative side effects from drug-drug interactions. The more medications a patient takes, the greater the likelihood that interactions between those drugs could trigger negative side effects, including long-term organ damage or even death. For the study, researchers designed an algorithm...
Gayle N. Scott, PharmD DISCLOSURES June 18, 2019 Lab tests play a key role in clinical decision-making. More than 4000 lab testsare available, and an estimated 70% of clinical decisions are based on their results. Correct interpretation is critical. The pharmacologic effects of drugs can change the results of lab tests; for example, levothyroxine increases thyroid levels, or lisinopril may increase potassium levels. But these changes do not involve...
