by Leigh Macmillan, Vanderbilt University The commonly used muscle relaxant tizanidine can lower blood pressure. Tizanidine is metabolized by the enzyme CYP1A2, and concurrent use of tizanidine and a CYP1A2 inhibitor, such as ciprofloxacin, greatly increases tizanidine plasma concentrations. Despite package insert warnings, tizanidine and CYP1A2 inhibitors are commonly co-prescribed. Cecilia Chung, MD, and colleagues used...
Tag: <span>drug interactions</span>
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Six surprising drug interactions you should know about
As the UK population grows older, more and more people are using a combination of drugs to treat multiple conditions. This can lead to interactions and side effects that we all need to be aware of. Not only can drugs interact with each other, but they can also interact with food and drink, as well...
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