Tag: <span>Drug repurposing</span>

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Combination treatment based on drug repurposing shows promise in the treatment of retinal degenerations

NEWS RELEASE 22-JUL-2024 Peer-Reviewed PublicationUNIVERSITY OF EASTERN FINLAND Drug repurposing shows promise in the treatment of retinal degenerations, according to a new study by an international team of researchers, published in Nature Communications. A combination treatment incorporating three existing drugs – tamsulosin, metoprolol and bromocriptine – slowed disease progression in pre-clinical retinopathy models. Drug repurposing...

Predicting correct dosage may improve success of drug repurposing
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Predicting correct dosage may improve success of drug repurposing

by Sarah Small, Pennsylvania State University Credit: Cell Reports Medicine (2023). DOI: 10.1016/j.xcrm.2023.101227Before a drug can be used to treat a disease, it must go through a lengthy and expensive trial process to prove both safety and effectiveness. By repurposing already-approved drugs, researchers can cut out the time and expense of the former step—sometimes. According to...

Study in mice shows genes may be altered through drug repurposing
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Study in mice shows genes may be altered through drug repurposing

by  University of Illinois at Chicago A representative eye of a PAX6 deficient mouse after treatment (right) showing a better-developed eye and clear cornea compared to a control treated PAX6 deficient mouse eye (left) showing a smaller eye with scarring and blood vessel growth. Credit: University of Illinois Chicago Researchers at the University of Illinois Chicago have...

Drug repurposing: Researchers find existing medications may fight coronavirus infection
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Drug repurposing: Researchers find existing medications may fight coronavirus infection

by  University of New Mexico Image of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). University of New Mexico researchers who combed through a “library” of previously approved drugs believe they have identified a medication with the potential to help speed a patient’s recovery from SARS-CoV-2 infection. “The gist of it is we think we found...