MASSACHUSETTS INSTITUTE OF TECHNOLOGY IMAGE: MIT CHEMISTS HAVE DISCOVERED HOW THE STRUCTURE OF THE EMRE TRANSPORTER CHANGES AS A COMPOUND MOVES THROUGH IT. AT LEFT IS THE TRANSPORTER STRUCTURE AT HIGH PH. AS THE PH DROPS (RIGHT), THE HELICES BEGIN TO TILT SO THAT THE CHANNEL IS MORE OPEN TOWARD THE OUTSIDE OF THE CELL,...
by Yale University Bone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: Wikipedia In a new study led by Yale Cancer Center, researchers have discovered a novel metabolic gatekeeper mechanism for leukemia. This mechanism depends on a molecule called PON2, which could lead to a new treatment for the disease. The findings were published...
NATIONAL RESEARCH COUNCIL OF SCIENCE & TECHNOLOGY IMAGE: THIS CANCER CELL SPECIFIC ANTI-CANCER DRUG PRECURSOR (SMAC-FRG-DOX) FORMED ITSELF BY HYDROPHOBIC INTERACTION WITHIN THE MOLECULE WITHOUT THE USE OF ADDITIONAL POLYMERS AND DRUG CARRIERS. Although the diverse treatment methods developed to effectively treat cancer, chemotherapy using anticancer agents has been proven especially effective in many clinical applications. Above...
Peptide also kills multidrug-resistant bacteria on its own NANYANG TECHNOLOGICAL UNIVERSITY SCIENTISTS AT NTU HAVE DEVELOPED A SYNTHETIC ANTIMICROBIAL PEPTIDE THAT MAKES DRUG-RESISTANT BACTERIA SENSITIVE TO ANTIBIOTICS AGAIN. ON ITS OWN, THE PEPTIDE CAN ALSO KILL BACTERIA THAT HAVE GROWN RESISTANT… view more CREDIT: NTU SINGAPORE Scientists at Nanyang Technological University, Singapore (NTU Singapore) have...
By Nick Lavars June 03, 2020 How the human species contends with an alarming rise in antibiotic-resistant bacteria is a pressing issue, with some experts predicting these superbugs could kill millions a year by 2050 if we don’t develop new weapons to neutralize the threat. A team of Princeton researchers has put forward a new...
Reviewed by Emily Henderson, B.Sc “Testing, testing, testing.” It’s a mantra that health officials have been constantly promoting because screening people for COVID-19 is the best way to contain its spread. In the U.S., however, that crucial necessity has been hampered due to a lack of supplies. But University of Utah electrical and computer engineering...
UNIVERSITY OF NOTRE DAME Using a new technique that can identify genetic profiles of individual cells, University of Notre Dame researchers modeled a breast cancer tumor’s potential resistance to a drug, and then identified a drug combination that reversed that resistance. Siyuan Zhang, the Dee Associate Professor of Biological Sciences at Notre Dame, and his...
POSTED BY SARAH MCQUATE-WASHINGTON Huan He examines how well bacteria grew on agar plates containing an antibiotic. (Credit: Mark Stone/U. Washington) Current water and wastewater disinfecting methods work well to deter bacterial growth, but have varied success in fighting an antibiotic resistance gene, according to new research. Each year, antibiotic-resistant bacteria infect at least 2 million...
New results presented at HIVR4P finds no dapivirine-associated resistance detected among women who acquired HIV while using dapivirine vaginal ring in ASPIRE MICROBICIDE TRIALS NETWORK MADRID, October 24, 2018 – A monthly vaginal ring that slowly releases an antiretroviral (ARV) drug called dapivirine is currently undergoing regulatory review. If approved, the dapivirine ring would be the first biomedical HIV prevention method developed...
The contentious “right to try” bill that President Trump signed into law to help terminally ill patients get access to treatments that might — I emphasize the “might” — cure them or prolong their lives is more wishful thinking that it is a reality. Human HeLa cells in culture. Recent advances in drug sensitivity and resistance testing suggest that it’s worth...
