Tag: <span>drug-resistant cancers</span>

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Scientists identify potential “weak spot” in drug-resistant cancers
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Scientists identify potential “weak spot” in drug-resistant cancers

By Michael Irving July 24, 2022 A new study uncovers a potential mechanism for fighting drug-resistant cancers Depositphotos Scientists in Spain have uncovered a mechanism behind why some cancer patients don’t respond well to treatments – and more importantly, found a “weak spot” that could be targeted by existing drugs. Frustratingly, many cancer patients don’t...

Double trouble for drug-resistant cancers
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Double trouble for drug-resistant cancers

by Zehan Yu,  Duke-NUS Medical School The team found that Wnt/beta-catenin pathways activate MYBL2 in the nucleus, which regulates several DNA repair genes. In healthy people, this helps maintain stem cells from accumulating mutations. But it can also help some cancers resist DNA damage by PARP inhibitors. These patients could benefit from receiving a drug that...