CHAMPAIGN, Ill. — By enticing away, the repressors dampening unexpressed, silent genes in Streptomyces bacteria, researchers at the University of Illinois have unlocked several large gene clusters for new natural products, according to a study published in the journal Nature Chemical Biology. Since many antibiotics, anti-cancer agents and other drugs have been derived from genes...
Tag: <span>Drug</span>
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FDA approves drug to treat rare immune disease
Gamifant is the first drug to be approved specifically for HLH. The drug’s efficacy was demonstrated in a clinical trial of 27 pediatric patients with suspected or confirmed primary HLH. Patients had refractory, recurrent, or progressive disease while being treated with conventional HLH therapy or were intolerant of conventional HLH therapy. Patients were a mean...
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Want to cut down on your meds? Your pharmacist can help.
Pharmacists are pivotal in the process of deprescribing risky medications in seniors, leading many to stop taking unnecessary sleeping pills, anti-inflammatories and other drugs, a new Canadian study has found. Published today in the Journal of the American Medical Society (JAMA), the study by researchers at Université de Montréal (UdeM) took place in Quebec, Canada....
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This tiny particle might change millions of lives
Nanoparticle targets kidney disease for drug delivery UNIVERSITY OF SOUTHERN CALIFORNIA Remember the scene in the movie Mission: Impossible when Tom Cruise has to sneak into the vault? He had to do all sorts of moves to avoid detection. That’s what it’s like to sneak a targeted drug into a kidney and keep it from...
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Why a patient paid a $285 copay for a $40 drug
Two years ago Gretchen Liu, 78, had a transient ischemic attack — which experts sometimes call a “mini-stroke” — while on a trip to China. After she recovered and returned home to San Francisco, her doctor prescribed a generic medication called telmisartan to help manage her blood pressure. Liu and her husband Z. Ming Ma,...
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FDA expands recall of blood pressure drug due to cancer concern
The US Food and Drug Administration expanded the list of drugs being recalled that contain valsartan. The drug is used as a component in a set of drugs used to treat heart failure and blood pressure. The FDA initially announced a valsartan recall in July after lab tests discovered that some drugs could have been...
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Positive Results For Ovid Drug, But Questions Remain
Michael Cecere’s child, Weston, is five years old. He struggles with daily living. He cannot speak, usually move by stroller or wheelchair, and only just learned to drink from a straw. The reason: a genetic deletion on his 15th chromosome, causing a condition called Angelman Syndrome, discovered after his mother noticed that he was missing developmental...
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Distrust of power influences choice of medical procedures
Complementary and alternative medicine benefit from the credence given to conspiracy theories and the associated skepticism towards existing power structures JOHANNES GUTENBERG UNIVERSITAET MAINZ IMAGE: INDIVIDUALS WITH A PRONOUNCED CONSPIRACY MENTALITY SEE NON-ESTABLISHED MEDICAL CONCEPTS, SUCH AS HOMEOPATHY, IN A MUCH MORE POSITIVE LIGHT AND TEND TO USE THESE MORE FREQUENTLY. First World countries have well-developed...
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Red-blood-cell ‘hitchhikers’ offer new way to transport drugs to specific targets
New drug delivery technology aims to decrease side effects and improve efficacy UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE PHILADELPHIA – A new drug-delivery technology which uses red blood cells (RBCs) to shuttle nano-scale drug carriers, called RBC-hitchhiking (RH), has been found in animal models to dramatically increase the concentration of drugs ferried precisely to selected...
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How cannabis and cannabis-based drugs harm your brain
Long-term use of either cannabis or cannabis-based drugs impairs memory say, researchers. The study has implications for both recreational users and people who use the drug to combat epilepsy, multiple sclerosis, and chronic pain LANCASTER UNIVERSITY Long-term use of either cannabis or cannabis-based drugs impairs memory say, researchers. The study has implications for both recreational...