Published: Jul. 09, 2023, 7:52 p.m. The injectable drug Ozempic is shown Saturday, July 1, 2023, in Houston. (AP Photo/David J. Phillip)AP By Leada Gore | [email protected] It’s typical advice given to someone undergoing a medical procedure involving general anesthesia: Don’t eat or drink anything for a period prior to the operation. Forgoing food or water is...
by University of California – San Diego Mouse pancreatic tumors were significantly smaller after being treated with a combination of KRAS inhibitor MRTX1133 and ERBB inhibitor Afatinib (bottom row), compared to no treatment (top row) or being treated with Afatinib (second row) or MRTX1133 (third and fourth rows) alone. Credit: UC San Diego Health Sciences Mutations...
Marine Cygler June 23, 2023 BORDEAUX, France — Could AEF0117, a drug that has a novel mechanism of action in the brain, be the drug to fight cannabis addiction? Results from a phase 2a clinical trial that examined the efficacy of AEF0117 in patients with cannabis use disorder have created quite a stir. The study was published in Nature...
by University of Edinburgh Scientists investigating potential drugs to improve recovery from spinal cord injury have uncovered a promising route to new treatments. Researchers tested more than 1,000 potential drugs and identified that an existing one—cimetidine—improved spinal repair in zebrafish. The drug also helped improve recovery of movement and reduce the extent of spinal cord damage...
UNIVERSITY OF BARCELONA IMAGE: PROFESSOR MANUEL VÁZQUEZ-CARRERA, FROM THE FACULTY OF PHARMACY AND FOOD SCIENCES OF THE UNIVERSITY OF BARCELONA AND THE INSTITUTE OF BIOMEDICINE OF THE UB (IBUB). CREDIT: UNIVERSITY OF BARCELONA There are still many enigmas about the mechanism of action of metformin, the most prescribed drug to treat diabetes mellitus, also known...
by Columbia University Irving Medical Center Effects of AEF0117 on mood after cannabis smoking in the Phase 2a study. The subscales of the 44-item VAS used to measure precipitated cannabis withdrawal: (a) Irritable, (b) Anxious, and (c) Miserable were also used to measure mood alterations after smoking cannabis. In this context, in the MMRM analysis performed...
by University of California, Los AngelesCredit: Pixabay/CC0 Public Domain Due to a policy decision in 2010 by the U.S. Food and Drug Administration (FDA), the price of a prescription for the therapeutic gout drug colchicine increased nearly 16-fold from $11.25 in 2009 to $190.49 in 2011. Out-of-pocket costs for patients who took the drug jumped more...
by American Academy of Neurology Credit: Pixabay/CC0 Public Domain The drug atogepant may help prevent migraines for people who have had no success with other preventive drugs, according to a preliminary study released April 20, 2023, which will be presented at the American Academy of Neurology’s 75th Annual Meeting being held in person in Boston and live...
Summary: A newly developed drug that blocks sodium channels in the cell membrane that can reverse MYT1L failure alleviates social behavior deficits in mouse models of ASD. Source: German Cancer Research Center The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists from the Hector Institute for Translational Brain Research (HITBR) have now found another molecular...
UNIVERSITY OF AUCKLAND The age-old quest for immortality has taken a step forward with the results of an Aotearoa New Zealand study just published in leading international journal Nature Ageing. The Waipapa Taumata Rau, University of Auckland trial demonstrates that long-term treatment of healthy mice from middle-age (one year) with a drug currently used to treat...
