by University of New South Wales The use of pregabalin, a medicine for neuropathic pain, is relatively common among a sample of people who regularly inject drugs (PWID) in Australia, a new study by researchers at the National Drug and Alcohol Research Center (NDARC), UNSW Sydney has found. In a sample of 905 participants from...
Drug that reduces swelling may help protect against brain and spinal cord injury. Every year, millions of people around the world suffer brain and spinal cord injuries resulting from trauma, accidents, infections, or stroke. These injuries trigger swelling that can lead to death or long-lasting disabilities, but current treatment options are limited and can be...
by Peter MacCallum Cancer Centre Researchers from Peter Mac have discovered an innovative way to dampen severe inflammation in mice, uncovering a potential new therapeutic approach for inflammatory and autoimmune conditions such as arthritis, psoriasis and liver disease, as well as some cancers. The research, co-led by Prof Mark Dawson’s laboratory, in collaboration with scientists...
Canadian researchers launched a study Monday into the use of a powerful anti-inflammatory drug to reduce the risks of pulmonary complications and death related to the new coronavirus. Several COVID-19 patients have had severe complications from a surge of activated immune cells in the lungs—known as a “cytokine storm.” In a cytokine storm, the immune...
UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES Sugars like polysaccharides are found everywhere in nature and are believed to be essential for life to arise. In humans, they cover the surface of all cells and the family of polysaccharides called GAGs (glycosaminoglycans) are particularly abundant and difficult to analyse. GAGs of the...
A combination of two previously studied osteoarthritis drugs works better than either drug alone, Salk researchers discovered People with osteoarthritis, or “wear and tear” arthritis, have limited treatment options: pain relievers or joint replacement surgery. Now, Salk researchers have discovered that a powerful combination of two experimental drugs reverses the cellular and molecular signs of...
by University of Manchester Two trials of a new drug have shown that at low doses, it can ease the often distressing symptoms of chronic cough with minimal side effects. Principle researcher Jacky Smith, a Professor of Respiratory Medicine at The University of Manchester and a consultant at Wythenshawe Hospital, says Gefapixant has the potential...
Using a type of genetic screen that had previously been impossible in the mammalian brain, MIT neuroscientists have identified hundreds of genes that are necessary for neuron survival. They also used the same approach to identify genes that protect against the toxic effects of a mutant protein that causes Huntington’s disease. These efforts yielded at...
A National Institutes of Health study found that chronic treatment with mirabegron, a drug approved to treat overactive bladder, activated brown fat in a small group of healthy women and had several other beneficial metabolic effects. Brown fat, or brown adipose tissue, is a form of fat that burns calories to generate heat. The research,...
by Gavin Churchyard, The Conversation Lengthy negotiations ended in good news recently when the price of rifapentine, a lifesaving antibiotic, was marked down by 66% by its manufacturer Sanofi. When combined with another antibiotic (isoniazid), rifapentine can prevent tuberculosis (TB) disease. The move was announced at the Union World Conference on Lung Health in October...
