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Parkinson’s drug changes the gut microbiome for the worse due to iron deficiency, study reveals

by University of Vienna Chemical imaging of active gut microbes. After brief incubation with heavy water, culture medium and a drug, various chemical bonds (here C–D and C–H) in the stool sample are shown in yellow and green, their ratio in yellow-purple (left). Selected microbes are detected in the same image section with fluorescence-labelled oligonucleotide...

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Parkinson’s may soon be treated with blood pressure drug

Isradipine, an antihypertensive drug, is emerging as a potential new treatment for Parkinson’s disease due to promising results of in vitro tests. Until now, it was unclear whether administering the drug in vivo would yield the same benefits — new research shows that it does. Isradipine is a calcium-channel inhibitor used to treat hypertension. Previous studies have...

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Half of those on Parkinson’s drugs may develop impulse control problems

Over time, half of the people taking certain drugs for Parkinson’s disease may develop impulse control disorders such as compulsive gambling, shopping or eating, according to a study published in the June 20, 2018, online issue of Neurology. Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease....