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Engineering an ‘invisible cloak’ for bacteria to deliver drugs to tumors
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Engineering an ‘invisible cloak’ for bacteria to deliver drugs to tumors

by Columbia University School of Engineering and Applied Science Probiotic bacteria (E. coli Nissle 1917 strain, green) is engineered to controllably evade immune system (macrophage, transparent) using a genetically encoded encapsulation system (capsular polysaccharides with circuit board, shown as transparent coating surrounding the bacterial cells). This system was used to enhance delivery of therapeutic bacteria...