by University of California – San Diego Credit: Unsplash/CC0 Public Domain In the first known study of its type, an international team of researchers evaluated whether high research and development (R&D) costs explain high drug prices in the United States. “There is a presumption that high R&D costs justify high drug prices. If that were...
by Singular Research Centers Network Co-localized version of “Isness” (“Isness-C”). Credit: David Glowacki A paper published in the journal Scientific Reports demonstrates how virtual reality group experiences can produce responses similar to those triggered by psychoactive drugs, such as hallucinogenic mushrooms or LSD. Describing the sensations that arose immediately following a left-hemisphere stroke, brain scientist...
by Medical Journal of Australia Credit: Pixabay/CC0 Public Domain Sodium–glucose cotransporter 2 (SGLT2) inhibitors, such as empagliflozin, dapagliflozin, canagliflozin and ertugliflozin, have been game changers in the treatment of type 2 diabetes, but their potential for closing the mortality gap in type 1 diabetes has been a regulatory minefield, according to the authors of a...
by Penn State College of Medicine Simulation studies comparing the performance of PUMICE to other TWAS methods. Panels (a, b) illustrates the comparison of PUMICE to other single-tissue TWAS methods for type I error (a) and power (b). Panels (c, d) illustrates the comparison of PUMICE to multi-tissue TWAS method (UTMOST) for type I error...
by C. Michael White, The Conversation Credit: Pixabay/CC0 Public Domain The Food and Drug Administration took 130 enforcement actions against counterfeit medication rings from 2016 through 2021, according to my new study published in the journal Annals of Pharmacotherapy. Such actions might involve arrests, confiscation of products or counterfeit rings being dissolved. These counterfeiting operations involved tens of millions...
by Mary Ann Liebert, Inc Prostate cancer cells. Credit: NIH Image Gallery A novel high-throughput screening assay is designed to identify inhibitors of the androgen receptor, which plays a critical role in the progression of prostate cancer. The assay could be used to identify new drugs to treat resistant forms of prostate cancer, as described...
UNIVERSITY OF VIRGINIA HEALTH SYSTEM IMAGE: “WE CAN NOW UNDERSTAND A NEW PRINCIPLE IN HOW PROTEINS CAN FORM THE SHELL THAT PACKAGES THE DNA IN A VIRUS,” SAID LEAD RESEARCHER EDWARD H. EGELMAN, PHD, OF THE UNIVERSITY OF VIRGINIA SCHOOL OF MEDICINE. “THIS HAS IMPLICATIONS FOR NOT ONLY UNDERSTANDING HOW CERTAIN VIRUSES EVOLVED BUT POTENTIALLY...
Heidi Ledford Researchers are studying the long-term effects of treatments given to people hospitalized with COVID-19. Credit: Diego Vara/Reuters In the early days of the COVID-19 pandemic, urologist and clinical epidemiologist Kari Tikkinen found his schedule full of cancelled surgeries, so he had some time to kill. “Do whatever you feel is most useful,” his...
25 March 2022 Researchers are trying to establish whether existing COVID-19 vaccines and treatments can prevent lasting symptoms. Heidi Ledford Researchers are studying the long-term effects of treatments given to people hospitalized with COVID-19.Credit: Diego Vara/Reuters In the early days of the COVID-19 pandemic, urologist and clinical epidemiologist Kari Tikkinen found his schedule full of...
CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) Inflammation is a defence mechanism of the body to fight pathogens. However, when it is widespread and excessive, it can aggravate the pathology and even cause death. One of the ways in which this excessive response occurs is called acytokine storm, an inflammatory process produced by these proteins, cytokines,...
