by Ananya Sen, University of Illinois at Urbana-Champaign Microscopy image of a T-cell population harboring a shortened form of the HIV virus that expresses a green fluorescent protein. Different drug treatments result in the various amounts of cell-to-cell variability in gene expression. Credit: Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign When...
MASSACHUSETTS GENERAL HOSPITAL BOSTON – New treatments for Alzheimer’s disease are desperately needed, but numerous clinical trials of investigational drugs have failed to generate promising options. Now a team at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) has developed an artificial intelligence-based method to screen currently available medications as possible treatments for Alzheimer’s...
DEUTSCHES PRIMATENZENTRUM (DPZ)/GERMAN PRIMATE CENTER IMAGE: DR. MARKUS HOFFMANN, SCIENTIST AT THE INFECTION BIOLOGY UNIT AT THE GERMAN PRIMATE CENTER (DPZ) – LEIBNIZ INSTITUTE FOR PRIMATE RESEARCH. CREDIT: KARIN TILCH There are no therapeutics available that have been developed for COVID-19 treatment. Repurposing of already available medication for COVID-19 therapy is an attractive option to...
Pictured is a brain section scan showing a glioblastoma tumor (in dark blue).Dr. P. Marazzi/Science Photo Library/Getty Images One of the most aggressive forms of brain cancer is glioblastoma, which has a low survival rate and is difficult to treat. One type of glioblastoma is mitochondrial brain cancer. This type relies on overactive mitochondria, or...
by Jonathan Gardner@ByJonGardner Jud Broadhurst was 14 years old when he began to notice the symptoms. Playing competitive soccer, Broadhurst would fall, seemingly “for no reason,” he said. But there was one, lurking in his genes. Broadhurst had a form of spinal muscular atrophy, a rare neuromuscular condition that was causing his muscles to weaken...
Researchers have found that a rheumatoid arthritis drug can help weaken superbugs, making older antibiotics effective againGiovanni_Cancemi/DepositphotosVIEW 1 IMAGES A virus might be the boogeyman of 2020, but we shouldn’t ignore bacteria as a looming health threat. The growing problem of antibiotic resistance isn’t slowing down, which could soon render our best drugs useless against infection. Now,...
Anticholinergic medications are used for many conditions but might also accelerate cognitive decline, especially in older persons with biological or genetic risk factors UNIVERSITY OF CALIFORNIA – SAN DIEGO A team of scientists, led by researchers at University of California San Diego School of Medicine, report that a class of drugs used for a broad...
by University of Cologne It is usually difficult to predict how well drugs will work when they are combined. Sometimes, two antibiotics increase their effect and inhibit the growth of bacteria more efficiently than expected. In other cases, the combined effect is weaker. Since there are many different ways of combining drugs—such as antibiotics—it is...
by Vanessa Wasta, Johns Hopkins University Photomicrograph of a mitochondrion, the energy-generating powerhouse in a human cell. Johns Hopkins Medicine researchers are studying how to recycle these organelles and perhaps, lead to new treatments for Parkinson’s disease. Credit: University of Wisconsin-Madison College of Agricultural and Life Sciences Researchers at Johns Hopkins Medicine are taking a...
Reviewed by Emily Henderson, B.Sc.Sep 3 2020 In a first of its kind study, a University of Houston researcher is examining two common drugs used for dementia in patients with Alzheimer’s disease to determine the extent to which they don’t mix well together and cause a cascading event of side effects, prompting the need for...
