by Elana Gotkine Two doses of recombinant zoster vaccine (RZV) are effective against herpes zoster (HZ), with the vaccine effectiveness (VE) of two doses waning a little over four years of follow-up, according to a study published online on Jan. 9 in the Annals of Internal Medicine. Ousseny Zerbo, Ph.D., from Kaiser Permanente Northern California...
by Amy Norton Newer oral medications for rheumatoid arthritis (RA) do work quite well in the “real world,” despite some doubts that they would, according to a new study. The study, of 622 adults with RA, found that most were doing well on medications called JAK inhibitors, a relatively new drug class for the arthritic...
Credit: Pixabay/CC0 Public Domain Pharmaceutical giant Eli Lilly said Thursday it will seek approval to add its diabetes drug to the buzzy US weight loss market after achieving promising results in a new clinical trial. Tirzepatide, currently approved to treat type 2 diabetes under the name Mounjaro, is taken once a week as an injection. Eli Lilly...
by Uppsala University Credit: Unsplash/CC0 Public Domain Patients treated with blood pressure-lowering drugs can experience much greater improvements from a change of medication than from doubling the dose of their current medication. This is shown by a new study from Uppsala University, published in the Journal of the American Medical Association (JAMA). In this study, 280 patients tested...
by Veterans Affairs Research Communications Credit: Pixabay/CC0 Public Domain A large Veterans Affairs (VA) clinical trial found that the blood pressure drug chlorthalidone (CTD) was not superior to hydrochlorothiazide (HCTZ) for the prevention of cardiovascular disease or non-cancer death. Both drugs are in a class of medications called thiazide diuretics, commonly known as water pills....
by University of Edinburgh Credit: Unsplash/CC0 Public Domain Medication that lowers blood pressure is equally effective if taken in the morning or evening, a large clinical trial has found. This overturns previous research that suggested blood pressure-lowering medication may be more effective if taken in the evening. Blood pressure-lowering medications are among the most widely prescribed...
by Northwestern University When mixed cortical cultures are established at P3, UMNs are labeled by eGFP expression in UCHL1-eGFP reporter mice, and express disease-causing proteins in reporter lines of mouse models of amyotrophic lateral sclerosis (ALS) (a-c) Generation of hSOD1G93A-UeGFP and WT-UeGFP littermate control mice. (d-e) UMNs in layer 5 of the primary motor cortex...
Serlopitant has potential as a therapy for the treatment of chronic pruritus, according to a study published in the May issue of the Journal of the American Academy of Dermatology. Gil Yosipovitch, M.D., from the University of Miami, and colleagues assessed the safety and efficacy of the P/neurokinin 1 receptor antagonist serlopitant in treating chronic pruritus...
