October 2, 2024 by Monash University Monash University researchers have discovered how the hormone peptide glucagon could better treat conditions such as obesity and type 2 diabetes, which affect billions of people. Glucagon—like insulin, from the pancreas—has been known about for 100 years, but the way it works is only beginning to be understood. An...
Tag: <span>endocrinology & metabolism</span>
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Protein discovery advances quest for treatment for age- and cancer-related muscle degeneration
September 26, 2024 by Duke-NUS Medical School Modifying DEAF1 levels can restore muscle function in aging or cachectic muscles by correcting imbalances in muscle stem cells. Credit: Tang Hong-Wen lab (using BioRender)With the global population aging rapidly, sarcopenia, a condition that affects millions of older adults and severely diminishes their quality of life, is emerging...
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New research finds higher levels of leptin indicate brain protection against late-life dementia
September 18, 2024 by University of Texas Health Science Center at San Antonio Credit: CC0 Public DomainNew research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults, according to a study by The University...
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Ozempic could curb progression of diabetes-linked liver disease
September 16, 2024 by Ernie Mundell Fatty liver disease linked to diabetes and obesity can easily progress to liver cirrhosis, but new research suggests that GLP-1 medicines like Ozempic can help stop that. In a new decades-long study, veterans with diabetes and what’s known as metabolic dysfunction-associated steatotic liver disease (MASLD) were 14% less likely...
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Nonsurgical procedure brings relief to those with thyroid nodules
September 18, 2024 by Rebecca Badeaux, UC Davis Credit: UC DavisTightness in the throat. Difficulty swallowing. A noticeable bump on your neck. These are the reasons why more than 40 people have sought out the expertise of endocrinological surgeon Claire Graves. Some have come from as far as Idaho for a procedure only available in...
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Exploring the possible link between PTSD and early menopause
September 10, 2024 by The North American Menopause Society Credit: Unsplash/CC0 Public DomainPost-traumatic stress disorder (PTSD) can cause an array of adverse mental health effects, but physical side effects are also common. A new study conducted with Persian Gulf War female military personnel demonstrates that women with probable PTSD are twice as likely to experience...
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Hormone therapy tied to less biological aging in postmenopausal women
September 4, 2024 by Lori Solomon Postmenopausal women who use hormone therapy (HT) are biologically younger than those not receiving HT, according to a study published online Aug. 29 in JAMA Network Open. Yufan Liu and Chenglong Li, Ph.D., from Peking University in Beijing, evaluated the association between HT use and discrepancies between chronological and...
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Novel pathway could lead to potential treatment for metabolic liver disease
August 30, 2024 by Hayley Mignacca, University of Massachusetts Medical School Lyz-IFNγR2−/− mice are rescued from fatty liver progression to MASH. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-49633-yResearch from the lab of Jason Kim, Ph.D., professor of molecular medicine and medicine, identified a novel pathway in the progression of metabolic liver disease that could be targeted...
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A new class of beige fat cells that burn energy via ‘futile cycles’ could lead to better metabolic health
August 14, 2024 by Fabio Bergamin, ETH Zurich Credit: Cell Metabolism (2024). DOI: 10.1016/j.cmet.2024.07.005Fat cells come in three colors: white, brown, and beige. White fat cells store fat in our body as an energy reserve. We need these cells, but having too many creates health problems. Brown fat cells are particularly active in infants. They...
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Eating for necessity or pleasure? There is a brain circuit for that
August 8, 2024 by Taylor Barnes, Baylor College of Medicine DBBPenk neurons are activated by food. Credit: Nature Metabolism (2024). DOI: 10.1038/s42255-024-01099-4People eat either because they are hungry or for pleasure, even in the absence of hunger. While hunger-driven eating is fundamental for survival, pleasure-driven feeding may accelerate the onset of obesity and associated metabolic...
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