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Enzyme checkpoint identified in tumor-associated macrophages
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Enzyme checkpoint identified in tumor-associated macrophages

by University of Vienna Immunofluorescence image of the expression of PHGDH (red) and CD3 T cells (green) in cryosectioned AE17 mesothelioma. Credit: Zhengnan CaiA study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in Cellular & Molecular Immunology, shows that the enzyme phosphoglycerate dehydrogenase (PHGDH) acts as a metabolic...