COLUMBIA UNIVERSITY IRVING MEDICAL CENTER EYEDROPS WITH A CASPASE-9 INHIBITOR PREVENT RETINAL INJURY FROM RETINAL VEIN OCCLUSION. IN THE LEFT IMAGE, RVO CAUSES SWELLING IN THE RETINA AND THE RETINAL LAYERS ARE LESS DISTINCT…. view more CREDIT: TROY LAB (CUIMC) NEW YORK, NY (June 29, 2020) — Researchers at Columbia University Irving Medical Center have...
by Hokkaido University Research into how the SARS-CoV-2 virus induces death is suggesting potential treatments for its most destructive complications. Leading immunologists in Japan are proposing a possible molecular mechanism that causes massive release of proinflammatory cytokines, or a cytokine storm, leading to the acute respiratory distress syndrome (ARDS) in COVID-19 patients. Their suggestions, published...
by Michael Addelman, University of Manchester Early results for a potentially revolutionary brain disease therapy given under compassionate use to a two-year-old has shown promise, a University of Manchester scientist will tell an international conference on Wednesday (13 May). Professor Brian Bigger will tell the American Society of Gene & Cell Therapy that the safety...
This news or article is intended for readers with certain scientific or professional knowledge in the field. Findings in Mice Point to New Approach That May Help Make Some Metastatic Breast Cancers Susceptible to Immunotherapy. In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found...
UC Riverside-led study could lead to the development of drugs that target liver and other cancers UNIVERSITY OF CALIFORNIA – RIVERSIDE RIVERSIDE, Calif. — RNA, or ribonucleic acid, is present in the cells of all living beings and required to synthesize proteins. A research team at the University of California, Riverside, has discovered the structure...
by Children’s Medical Research Institute Faster cancer treatments may be possible thanks to research from Children’s Medical Research Institute (CMRI). Researchers were surprised to discover a new way that an enzyme in cancer cells, telomerase, acts to keep cancer cells multiplying. This could mean a faster way to stop cancer cells in their tracks. Tracy Bryan, the lead author on research released in Science Advances, was initially skeptical of the findings. “We were very surprised at the...
By Jamie Eske Reviewed by Shilpa Amin MD, CAQ, FAAFP Methylenetetrahydrofolate reductase, or MTHFR, is an enzyme that breaks down the amino acids homocysteine and folate. The MTHFR gene that codes for this enzyme has the potential to mutate, which can either interfere with the enzyme’s ability to function normally or completely inactivate it. People have...
The study was published in the Journal of Nutritional Biochemistry CLEMSON UNIVERSITY CLEMSON, South Carolina – Researchers from Clemson University’s Environmental Toxicology Program have published research connecting an enzyme associated with detoxification to obesity and fatty liver disease, especially in males. William Baldwin, professor and graduate program coordinator in the College of Science’s department of biological sciences, and members of his laboratory used a novel mouse model...
Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis. The discovery was made by an international team of researchers using macromolecular neutron crystallography at the Department of...
Writing in the January 3 issue of Cancer Cell, researchers at University of California San Diego School of Medicine report that detection of “copy editing” by a stem cell enzyme called ADAR1, which is active in more than 20 tumor types, may provide a kind of molecular radar for early detection of malignancies and represent...
