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Good news for menopausal women taking hop supplements: Tests show no drug interactions
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Good news for menopausal women taking hop supplements: Tests show no drug interactions

CORVALLIS, Ore. – Hop-based dietary supplements that many women use to ease the night sweats and hot flashes commonly reported during menopause aren’t likely to cause drug interactions, new research from Oregon State University’s Linus Pauling Institute and College of Pharmacy shows. The findings are important because while hormone replacement therapy remains the standard of...

SMART researchers uncover new anti-phage defence mechanisms in bacteria
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SMART researchers uncover new anti-phage defence mechanisms in bacteria

Groundbreaking discovery explains why some bacteria have been able to defend against phage therapy, and opens new ways for the medical community to overcome existing challenges Singapore, 6 May 2020 – Researchers from Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, have discovered a new anti-phage defence mechanism found in some...

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New understanding of antibiotic synthesis

Researchers at McGill University’s Faculty of Medicine have made important strides in understanding the functioning of enzymes that play an integral role in the production of antibiotics and other therapeutics. Their findings are published in Science. “Many of the medicines that we rely on today are natural products, made by the Earth’s flora,” explains Dr....

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Researchers make breakthrough in understanding enzymes that assemble the antibiotic enacyloxin

Reviewed by James Ives, M.Psych. (Editor) One of the WHO’s three critical priority pathogens, Acinetobacter baumannii, for which new antibiotics are urgently needed is one step closer to being tackled, as researchers from the Department of Chemistry – University of Warwick have made a breakthrough in understanding the enzymes that assemble the antibiotic enacyloxin. Acinetobacter...

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Enzymes engineered to trap reaction intermediates

Many enzymatic processes involve a mechanism in which reaction intermediates are covalently attached to the enzyme’s active site. A strategy has been devised that enables mimics of these intermediates to be visualized.  Andrew M. Gulick Enzyme structure and function are routinely studied by altering the DNA that encodes the enzyme, thus replacing specific amino-acid residues in the enzyme with other...

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Enzymes in the cross-hairs

New strategies in the battle against antibiotic resistance TECHNICAL UNIVERSITY OF MUNICH (TUM) More and more bacteria are resistant to available antibiotics. A team of chemists from the Technical University of Munich (TUM) now presents a new approach: they have identified important enzymes in the metabolism of staphylococci. Blocking these enzymes in a targeted manner...

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New cancer treatment uses enzymes to boost immune system and fight back

UT Austin Engineers develop new way to treat cancer using enzyme therapy UNIVERSITY OF TEXAS AT AUSTIN AUSTIN, Texas — Researchers at The University of Texas at Austin have developed a new approach to treating cancer using enzyme therapy. The enzyme, PEG-KYNase, does not directly kill cancer cells but instead empowers the immune system to...

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Enzymes team up with light-activated catalysts

Catalysts working in pairs can promote more-effective reactions than can the same catalysts used sequentially. The coupling of an enzyme with a light-activated catalyst offers great potential for organic synthesis. Nicholas J. Turner The development of catalytic reactions is a dominant theme in chemistry, especially in industry, where major efforts are underway to develop large-scale...

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Manipulated enzymes

TU Graz researchers set milestone in biocatalysis research GRAZ UNIVERSITY OF TECHNOLOGY TU Graz researchers managed for the first time ever to ‘retrain’ an enzyme to build ring-shaped molecular structures instead of performing its natural task of reducing double bonds. The work was published in Angewandte Chemie, and is relevant for the production of pharmaceuticals and plant protection products. IMAGE: KATHRIN HECKENBICHLER...

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