Tag: <span>epigenetic information</span>

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Loss of epigenetic information can drive aging, restoration can reverse it
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Loss of epigenetic information can drive aging, restoration can reverse it

by Stephanie Dutchen, Harvard Medical School Credit: Cell (2023). DOI: 10.1016/j.cell.2022.12.027 An international study 13 years in the making demonstrates for the first time that degradation in the way DNA is organized and regulated—known as epigenetics—can drive aging in an organism, independently of changes to the genetic code itself. The work shows that a breakdown in epigenetic...

Technique allows mapping of epigenetic information in single cells at scale
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Technique allows mapping of epigenetic information in single cells at scale

Histones are tiny proteins that bind to DNA and hold information that can help turn on or off individual genes. Researchers at Karolinska Institutet have developed a technique that makes it possible to examine how different versions of histones bind to the genome in tens of thousands of individual cells simultaneously. The technique was applied to the...