YUVAN RESEARCH INC. IMAGE: HIGH-RESOLUTION DERMAL ULTRASOUND SCAN OF ONE OF THE CLINICAL TRIAL VOLUNTEERS COMPARING THE INITIAL SKIN TO 3 MONTHS OF THE GHK-CU GEL USE. THE BRIGHTER THE IMAGE, THE HIGHER THE COLLAGEN DENSITY. CREDIT: © 2023 YUVAN RESEARCH INC. Skin loses collagen and elastin and becomes progressively thinner with age leading to wrinkles, so...
Tag: <span>epigenetic mechanism</span>
Epigenetic mechanism associated with clinical outcome and therapeutic vulnerability in liver cancer
by Josep Carreras Leukaemia Research Institute NSUN7 epigenetic loss occurs in human primary HCC tumors in association with worse clinical outcome. (A) Percentage of NSUN7 methylation in the TCGA data set of primary tumors according to cancer type. (B) NSUN7 methylation is inversely correlated with NSUN7 transcript expression in TCGA HCC tumors. (C) NSUN7 methylation is...
Hidden epigenetic mechanisms behind chronic UTIs found
by Justin Jackson, Medical Xpress The culture of USCs of juvenile C3H/HeN mice regenerates differentiated urothelium in vitro. a, USCs isolated from 8-week-old C3H/HeN mice were expanded by spheroidal culture in matrigel with 50% L-WRN conditioned media (CM) including Y-27632, a ROCK inhibitor, and SB431542, a TGF β type 1 inhibitor. After 3 d of spheroid...
The epigenetic mechanism by which vitamin D modulates the tolerance of the immune system
by Josep Carreras Leukaemia Research Institute Dr. Esteban Ballestar at the Josep Carreras Leukaemia Research Institute. Credit: Josep Carreras Leukaemia Research Institute In autoimmunity, the mechanisms that guarantee that our defense system does not attack our own body—tolerance to oneself—does not work properly. Multiple sclerosis, which affects one in every 1,000 people in Spain, is...
Uncovering epigenetic mechanisms regulating glioma growth
by Melissa Rohman, Northwestern University Glioma of the left parietal lobe. CT scan with contrast enhancement. Credit: Mikhail Kalinin/CC BY-SA 3.0 Northwestern Medicine investigators have discovered the epigenetic mechanisms involved in the regulation of multiple oncogenes in glioma cells, mechanisms that promote overall glioma tumor growth and resistance to therapy, according to a study published in...