CREDIT: DR MANEL ESTELLER Scientists have used 3D models to break down the DNA behavior of cancer cells, in a breakthrough new study which could revolutionize treatment for the disease. In what is a first for science, a research team led by Dr Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute (IJC), demonstrated...
by C. David Allis, Rockefeller University Scientists are increasingly tracing a variety of diseases back to the so-called epigenome, a type of indexing system imposed on DNA that dictates how genes should be read by the cells. Now, a new study finds that changes in two epigenetics mechanisms—DNA and histone methylation—may interact to spur disease. The...
Triggers in everyday life such as running into a former drinking buddy, walking by a once- familiar bar, and attending social gatherings can all cause recovering alcoholics to “fall off the wagon.” About 40 to 60 percent of people who have gone through treatment for substance abuse will experience some kind of relapse, according to...
by University of California, Irvine Can your liver sense when you’re staring at a television screen or cellphone late at night? Apparently so, and when such activity is detected, the organ can throw your circadian rhythms out of whack, leaving you more susceptible to health problems. That’s one of the takeaways from two new studies by...
NEW YORK, February 28, 2019 – Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers. Now, a newly published paper featured on the March cover of the journal Brain adds significantly to this work by detailing how metabolites can be...
Spinal cord. The unpleasant sensation sparked by the nervous system when confronted with a harmful stimulus can be alleviated by blocking a genetic marker that switches off the activity of the neurons involved. Jose Vicente Torres Pérez, a Spanish researcher who works at Imperial College in London, has trialled this innovative pain relief therapy on...
