by Yale University a, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm. b–e, OARSI score (b), osteophyte development (c), subchondral bone plate (SBP) thickness (d) and synovitis score (e) in indicated mice 12 weeks after DMM (n = 8). f, Traces of open field testing at 12...
by Indiana University School of Medicine Pharmacokinetic analysis of levetiracetam (LEV) in 6-month aged 5XFAD mice reveals significant sex differences. A, Plasma concentration time profiles of LEV by dose and sex in 5XFAD males and females. B, One-compartment model fit for the 30 mg/kg dose. C, Volume of distribution (V/F) and clearance (CL/F) is shown....
Lyrica relieves a seizure-like phenomenon believed to be the cause of migraines It works by stopping a wave of brain cells, preventing symptoms, scientists say And it was found to boost calcium levels, with low amounts causing headaches A drug used to treat epilepsy could end the migraine misery for millions of sufferers, scientists claim....
