By Paul McClure Researchers have found that keto-induced changes in gut microbial makeup may be beneficial for epileptics Depositphotos A new UCLA study has found how a keto diet induces changes in the gut microbiome that could protect treatment-resistant epileptic children against seizures. The discovery could lead to the development of new therapeutic approaches. Evidence suggests...
by NYU Langone Health This microscope image of the brain region called the hippocampus shows the protein targeted by cannabis-derived CBD, GPR55 (red), and brain cells (blue) that send their extensions out to form the layers seen in the image. The interconnected nature of the hippocampus makes it a major site of for the initiation...
INSTITUT DU CERVEAU (PARIS BRAIN INSTITUTE) An unprecedentedly precise exploration of the molecular and electrophysiological basis of a form of autoimmune encephalitis, conducted by the “Cellular Excitability and Neuronal Network Dynamics” team at the Paris Brain Institute, elucidates for the first time a scenario for the onset of epileptic seizures in this pathology. The results, published...
by Colorado State University Credit: Pixabay/CC0 Public Domain Epilepsy, a chronic brain disorder that causes seizures, affects around 50 million people worldwide. New research from the lab of Department of Biomedical Sciences Professor Susan Tsunoda that was recently featured in the Journal of Neuroscience showed for the first time that a channel in the brain called dSlo2...
by Purdue University Credit: Pixabay/CC0 Public Domain Autism affects about 2% of children in the United States, and about 30% of these children have seizures. Recent large-scale genetic studies have revealed that genetic variants in a sodium channel, called voltage-gated sodium channel Nav1.2, are a leading cause of autism. Overactive sodium channels in the neuron cause...
THE KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KAIST) IMAGE: NEURONS CARRYING SOMATIC MUTATIONS IN MTOR LEAD TO FOCAL EPILEPTOGENESIS VIA NON-CELL AUTONOMOUS HYPEREXCITABILITY OF NEARBY NON-MUTATED NEURONS. (LEFT) NEURONS WITH MTOR MUTATION (GREEN) OBSERVED IN A MOUSE BRAIN SECTION IMAGE. (MIDDLE) NETWORK MODEL CONSISTING OF A SMALL PORTION OF MUTATED AND A LARGE PORTION...
by Linköping University Nina Ottosson is one of the researchers at Linköping University who have studied the effect of different molecules on ion channels. Credit: Thor Balkhed/LiU New molecules, developed by researchers at Linköping University, Sweden, have promising properties as possible drugs against epilepsy. A study published in the journal Epilepsia shows that several of the molecules have...
A team of researchers from the Florida State University College of Medicine has found that an amino acid produced by the brain could play a crucial role in preventing a type of epileptic seizure. Temporal lobe epileptic seizures are debilitating and can cause lasting damage in patients, including neuronal death and loss of neuron function. Sanjay Kumar,...
by University of Illinois at Chicago The DUSP4 protein is located on the border between epileptic and non-epileptic brain tissue Epileptic seizures often originate in small, localized areas of the brain where neurons abnormally fire in unison. These electrical impulses disrupt proper brain functioning and cause seizures. But what makes regions where seizures start different from...
MEDGADGET EDITORS MEDICINE, NEUROLOGY, NEUROSURGERY AptarGroup, a company based outside of Chicago, Illinois, has announced that the FDA recently approved a medication (NAYZILAM (midazolam)) for treatment of acute repetitive epileptic seizures and that the company’s Unidose Liquid System was chosen as the delivery mechanism for this rescue drug. The Unidose Liquid System doesn’t require priming and can be...
