by University of Edinburgh Micrograph showing cortical pseudolaminar necrosis, a finding seen in strokes on medical imaging and at autopsy. H&E-LFB stain. Credit: Nephron/Wikipedia People who experience a type of stroke linked with nearly half of all dementias could be treated for the first time by repurposing two cheap and common drugs, a trial shows. Researchers found that...
by Wellcome Trust Sanger Institute Credit: Omer Bayraktar & Kenny Roberts The most comprehensive study of kidney cancer at single-cell level has discovered a potential drug target to treat renal cell carcinoma, a cancer with a high mortality rate that is hard to detect. Researchers from the Wellcome Sanger Institute, the University of Cambridge and...
Cancer occurs when there is a genetic defect which spreads as cells divide. Modern science has tools to detect those genetic genes and maybe we will be able to fix them some day. Scientists at the University of Birmingham and Queen’s University Belfast have revealed that a defective gene normally found in blood cancers could be...
by University of Michigan Credit: Pixabay/CC0 Public Domain Since the beginning of the pandemic, researchers worldwide have been looking for ways to treat COVID-19. And while the COVID-19 vaccines represent the best measure to prevent the disease, therapies for those who do get infected remain in short supply. A new groundbreaking study from U-M reveals several drug contenders...
by The Scripps Research Institute A researcher at Calibr, the drug discovery division of Scripps Research, working in the high-throughput screening facility used to identify potential COVID-19 therapies. Credit: Scripps Research Mining the world’s most comprehensive drug repurposing collection for COVID-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that’s driving the...
New research examines a potential new approach to treating severe gout. Boy_Anupong/Getty Images Gout is a form of arthritis that results from excess uric acid in the bloodstream and causes intense pain, swelling, and stiffness around a joint. Doctors often treat severe gout with pegloticase (Krystexxa), a medication that reduces uric acid levels, but the...
by University Health Network Dr. Benjamin Haibe-Kains is the joint corresponding author for the study “Biological and therapeutic implications of a unique subtype of NPM1 mutated AML”, published in Nature Communications. Credit: The Princess Margaret Cancer Foundation Using advanced RNA sequencing, scientists have identified two unique subtypes of a prominent mutation present in many patients with Acute...
by University of Montreal Credit: CC0 Public Domain Several drugs already approved by the U.S. Food and Drug Administration (FDA) could potentially be used to alleviate the symptoms of COVID-19, biomedical researchers at Université de Montréal have found. The team—led by doctoral student Nehme El-Hachem, working under the supervision of UdeM pharmcology associate professor Moutih Rafei in collaboration...
