by Robert Langreth and Gerry Smith, Bloomberg News Credit: Unsplash/CC0 Public DomainAn experimental version of Eisai Co’s Alzheimer’s drug that might be given in patients’ homes exceeded the power of Leqembi, its approved infused formulation, in an early study that could pave the way to bolstering uptake. After six months of treatment, an injected form...
by Johns Hopkins University School of Medicine Artistic rendition of diabetic eye disease highlighting vascular changes (i.e., retinal neovascularization) observed in patients with proliferative diabetic retinopathy. Credit: Isabella S. Sodhi, McDonogh School Researchers at Wilmer Eye Institute, Johns Hopkins Medicine say they have evidence that an experimental drug may prevent or slow vision loss in people with...
by Delthia Ricks, Medical Xpress TCS2 protein reduction in SMA-positive areas in small PAs from SM22-Tsc+/- mice. a: SM22-Cre mice were bred with Tsc2flox/flox mice to generate SM22-Tsc+/- mice. b: Immunohistochemical analysis of lung tissue sections of SM22-Tsc2+/- mice to detect TSC2 (red), smooth muscle α-actin (SMA) (green), and DAPI (blue). Representative images from n=5 WT and 7 SM22-Tsc2+/- mice...
by Denise Mann An experimental drug that has been shown to treat rashes in people with lupus may also help with lupus-related joint pain. Affecting as many as 1.5 million people in the United States, lupus is an autoimmune disease in which the body’s immune system misfires against its own joints, skin, brain, lungs, kidneys and blood...
by Washington University School of Medicine Nanoparticles (red) are taken up by immune cells (green with blue nuclei). Researchers at Washington University School of Medicine in St. Louis have shown that an experimental nanoparticle-based drug therapy protects mice from sudden death due to the rupture of a major blood vessel in the abdomen, pointing the...
ALBERT EINSTEIN COLLEGE OF MEDICINE IMAGE: ANA MARIA CUERVO, M.D., PH.D. CREDIT: ALBERT EINSTEIN COLLEGE OF MEDICINE April 22, 2021–(BRONX, NY)–Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer’s disease in mice. The drug works by reinvigorating a cellular cleaning mechanism that gets rid of unwanted proteins by digesting...
A team of scientists led by Paul Dent, Ph.D., at Virginia Commonwealth University Massey Cancer Center has discovered that an experimental cancer drug called AR-12 inhibits the SARS-CoV-2 virus, the cause of the COVID-19 pandemic, from infecting cells and replicating. Their findings were published online today in the journal Biochemical Pharmacology, and steps are now being...
