Peer-Reviewed Publication MASS GENERAL BRIGHAM Myosteatosis, or aging-related fat accumulation in skeletal muscles, is a leading cause of declines in muscle strength and quality of life in elderly adults. Older adults who are sedentary and develop accumulated fat in the skeletal muscle are often prescribed exercise by their doctors to combat the condition. If scientists...
Tag: <span>fat accumulation</span>
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The fat tax: Long-term, systemic antibiotic use for the treatment of adolescent acne can promote fat accumulation
MEDICAL UNIVERSITY OF SOUTH CAROLINA IMAGE: MINOCYCLINE TREATMENT (RIGHT) INCREASED ABDOMINAL ADIPOSITY, COMPARED TO CONTROLS (LEFT). YELLOW = SUBCUTANEOUS ADIPOSE; GREEN = VISCERAL ADIPOSE. CREDIT: MATTHEW CARSON AND DR. CHAD NOVINCE OF THE MEDICAL UNIVERSITY OF SOUTH CAROLINA. A growing body of evidence is showing that the healthy gut microbiome – a community of microorganisms that live...
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RNA quality control system goes awry in frontotemporal lobar degeneration
by Osaka University Researchers at Osaka University have identified a fault in the RNA quality control system of cells that leads to the haywire production of toxic proteins in frontotemporal lobar degeneration and amyotrophic lateral sclerosis (FTLD/ALS). Their new study, published in the EMBO Journal, shows that an abnormality of the C9orf72 gene produces toxic...
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Fatty liver disease despite a normal weight
Researchers from the University of Tsukuba identify differences in the clinical features of non-obese patients with non-alcoholic fatter liver disease based on their sex and body mass index UNIVERSITY OF TSUKUBA REPRESENTATIVE MAGNETIC RESONANCE IMAGES OF THE FEMORAL REGION IN A FEMALE SUBJECT WITHOUT NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) (A) AND THAT IN A FEMALE...
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Brain imaging can predict Alzheimer’s-related memory loss
by Karolinska Institutet Researchers at Karolinska Institutet have imaged tau protein in the brains of living patients with Alzheimer’s disease. The amount and spread of tau proved a predictor of future memory loss. Brain imaging for measuring tau can be useful both for improving diagnosis and for developing more effective treatments, say the researchers. The...
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Researchers Identify Novel Genetic Variants Linked to Type-2 Diabetes
After examining the genes of more than 200,000 people all over the world who have type-2 diabetes, researchers from the Perelman School of Medicine at the University of Pennsylvania and the Veterans Health Administration’s (VHA) Corporal Michael J. Crescenz Veterans Affairs Medical Center (CMCVAMC) found hundreds of genetic variants never before linked to the disease....
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Biochemical alterations revealed in patients with Lesch-Nyhan disease
UNIVERSITAT AUTONOMA DE BARCELONA An international study by the Institute of Neuroscience of the UAB (INC-UAB), Emory University and Hospital Universitario La Paz, published in the PNAS journal, shows that patients suffering from Lesch-Nyhan, a rare neurological disease, present biochemical alterations in skin cells (fibroblasts), urine and cerebrospinal fluid. Researchers have also discovered why these...
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Fat accumulations in airways of obese people detected for first time
By Rich Haridy | October 20, 2019 A novel study has for the first time detected significant accumulations of fatty tissue in airway walls of obese and overweight people. The new research suggests these fat accumulations could explain why overweight individuals are at higher risk of respiratory disease and asthma. “Being overweight or obese has already been linked to having asthma or having worse asthma symptoms,” explains Peter Noble,...
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Researchers uncover gene that regulates fat accumulation and obesity
With both a normal diet, and a a high-fat diet, a lack of Panx1 increases cell size. Top rows show lower magnification (scale bar = 0.1 mm) and bottom rows are the insets showing higher magnification of the same image (scale bar = 0.05 mm). B. Credit: University of Western Ontario As obesity continues to...