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Researchers identify a key enzyme that controls white-to-brown fat conversion
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Researchers identify a key enzyme that controls white-to-brown fat conversion

by Jacqueline Mitchell, Beth Israel Deaconess Medical Center CUL2 controls PRDM16 protein stability and beige fat biogenesis. a, Immunoblotting of Flag-tagged PRDM16 protein in HEK293T cells co-expressing Myc-tagged cullin proteins or an empty vector (Vec). b, Immunoblotting of endogenous PRDM16 protein in inguinal adipocytes overexpressing (OE) Flag-tagged CUL2 or Vec. β-Actin was used as the loading control. c,...