Tag: <span>fatal organ dysfunctions</span>

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MicroRNA-34a Promotes Vascular Cellular Senescence and Consequent Calcification
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MicroRNA-34a Promotes Vascular Cellular Senescence and Consequent Calcification

With the growing interest in the accumulation of senescent cells as an important cause of aging, and more funding flowing into this part of the field, researchers are uncovering numerous direct links between cellular senescence and age-related conditions. Senescent cells cause harm to tissues via their inflammatory secretions, the senescence-associated secretory phenotype (SASP). The SASP...

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Chronic stress induces fatal organ dysfunctions via a new neural circuit

Micro inflammation developed at specific sites in the brain (top panel). Pathological analysis of the stomach showed damage to tissues in the stomach (bottom right) compared to mice not under stressful conditions (bottom left). New research reveals the mechanisms behind the effects of chronic stress and tiny inflammations in the brain on fatal gut failure....